Browse our latest Neuroscience articles

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    1. Neuroscience

    Automatic learning mechanisms for flexible human locomotion

    Cris Rossi, Kristan Leech ... Amy J Bastian
    A flexible but automatic stimulus-response mapping mechanism complements forward model recalibration in walking adaptation, immediately accounting for perceived changes in the environment through perception altered by the same recalibration process.
    1. Neuroscience

    Information, certainty, and learning

    Justin A Harris, Charles Randy Gallistel
    The acquisition and expression of Pavlovian conditioned responding are shown to be lawfully related to objectively specifiable temporal properties of the events the animal is learning about.
    1. Neuroscience

    Causal evidence for a domain-specific role of left superior frontal sulcus in human perceptual decision-making

    Miguel Barretto-Garcia, Marcus Grueschow ... Christian C Ruff
    Disrupting left superior frontal sulcus selectively impaired perceptual but not value-based decisions, revealing segregated prefrontal circuits for integrating sensory evidence versus subjective preferences in human choice behaviour.
    1. Neuroscience

    A forebrain hub for cautious actions via the midbrain

    Ji Zhou, Muhammad Sarmad Sajid ... Manuel A Castro-Alamancos
    Cautious action timing under threat depends on glutamatergic signaling from the subthalamic nucleus to the midbrain, revealing a circuit mechanism for adaptive goal-directed behavior.
    1. Neuroscience

    Human brain dynamics and spatiotemporal trajectories during threat processing

    Joyneel Misra, Luiz Pessoa
    Intrinsic neural attractors and extrinsic environmental inputs jointly steer the dynamic trajectories of brain activity during threat processing.
    1. Neuroscience

    Identifying regulators of associative learning using a protein-labelling approach in Caenorhabditis elegans

    Aelon Rahmani, Anna McMillen ... Yee Lian Chew
    An innovative and scalable proximity labelling method profiled proteins present in the Caenorhabditis elegans brain during learning, identifying known regulators as well as novel biological pathways.
    1. Neuroscience

    Executive resources shape the impact of language predictability across the adult lifespan

    Merle Marie Schuckart, Sandra Martin ... Jonas Obleser
    Analyses of self-paced reading times reveal that linguistic prediction deteriorates under limited executive resources, with this resource sensitivity becoming markedly more pronounced with advancing age.
    1. Neuroscience

    Synaptic mechanisms modulate the spatiotemporal dynamics of striatal direct pathway neurons and motor output

    John J Marshall, Jian Xu ... Anis Contractor
    Bidirectional modulation of the activity of the synaptic protein mGluR5 alters spontaneous mouse motor behavior and produces correlated changes in co-activity patterns among direct pathway neurons in the dorsal striatum.
    1. Neuroscience

    Inhibitory circuits control leg movements during Drosophila grooming

    Durafshan Sakeena Syed, Primoz Ravbar, Julie H Simpson
    Anatomical and behavioral characterization of inhibitory neurons in the Drosophila ventral nerve cord shows their critical, diverse roles in limb coordination.
    1. Immunology and Inflammation
    2. Neuroscience

    Microglia replacement by ER-Hoxb8 conditionally immortalized macrophages provides insight into Aicardi–Goutières syndrome neuropathology

    Kelsey M Nemec, Genevieve Uy ... F Chris Bennett
    A microglia replacement approach demonstrates that brain macrophages with patient mutations from Aicardi–Goutières syndrome, a genetic, brain predominant interferonopathy, are sufficient to drive interferon responses.