The N-terminus of the FGF14b isoform promotes the inactivation of voltage-gated Na+ channels to regulate the resurgent Na+ channel current needed for high frequency action potentials.
A comprehensive synapse-level analysis of a fly central-brain region has led to the identification of molecules that are necessary for mediating the normal density of connections.
Cells within the retina synchronize transmitter release across their output synapses in the dark, reducing the impact of noise generated at these synapses and allowing light-dependent signals to be transmitted with minimal added synaptic noise.
Empirical evidence suggests that the hippocampus constructs maps of spatial environments based on the relative locations of places (i.e., topology), rather than absolute distances and coordinates (i.e., geometry).
Farzaneh Najafi, Andrea Giovannucci ... Javier F Medina
Sensory-driven calcium spikes in Purkinje cells are not binary; instead, they are graded and can provide information about the strength of a periocular airpuff stimulus known to drive learning.
A protein within the nuclear membrane, MAN1, controls the expression of the circadian clock gene, BMAL1, in an example of cross-talk between two major gene regulatory pathways.