Kosuke Hamaguchi, Katherine A Tschida ... Richard Mooney
Intracellular recordings in singing birds and images of synapses in deafened birds provide insights into the neural circuitry that enables songbirds to fine-tune their songs.
Protein kinase C brings about post-tetanic potentiation - a temporary increase in synaptic strength due to increased transmitter release - via phosphorylation of a target protein, Munc18-1.
A gene found in Drosophila, and named redeye, encodes a protein that accumulates during sleep deprivation and forms part of the homeostatic system that promotes and maintains sleep.
Alexander M Herman, Longwen Huang ... Benjamin R Arenkiel
Optogenetic techniques, whereby light is used to activate neuronal cells, are quickly becoming widely used in neuroscience; but excessive exposure to light can actually silence certain types of neuronal cells.
Daine R Lesniak, Kara L Marshall ... Ellen A Lumpkin
Computer simulations show that the firing patterns of branched touch receptors can be set in part by the organization of their sensory endings in the skin.
Rishidev Chaudhuri, Alberto Bernacchia, Xiao-Jing Wang
Specific types of heterogeneity in the connectivity profile of a biological network give rise to dynamics with a hierarchy of localized temporal scales.
PTBP2 ensures that adult protein variants are expressed only in mature neurons through regulation of alternative splicing during early neuronal development.
