Climbing fiber activity gates the acquisition phase of motor learning but becomes nonessential for memory consolidation or performance once proficiency is achieved.
A novel point assignment method achieves 80% f1-score in single-neuron reconstruction across broad brain regions, enabling high-throughput brain-wide projection mapping.
Bárbara Pinto-Correia, Patrícia Caldeira-Bernardo, Miguel Remondes
Light-activating a proton pump (eArchT) to silence hippocampal synaptic terminals in the rodent retrosplenial cortex caused a spatial working memory impairment affecting interleaved trials where no light was delivered.
Reversible synaptic plasticity between sensory neurons and interneurons, switching between inhibitory and excitatory, underpins the neural basis of salt concentration memory-dependent preference reversal in Caenorhabditis elegans.
Alexander L Tesmer, Paulius Viskaitis ... Denis Burdakov
Orexin neurons precisely track body movement across behavioral and metabolic states, revealing a neural mechanism that links motor activity to arousal and energy resources.
