Browse our latest Neuroscience articles

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    1. Neuroscience

    Deletion of Neuroligins from Astrocytes Does Not Detectably Alter Synapse Numbers or Astrocyte Cytoarchitecture by Maturity

    Samantha R Golf, Justin H Trotter ... Thomas C Südhof
    Revised
    Reviewed Preprint v3
    Updated
    • Fundamental
    • Compelling
    1. Developmental Biology
    2. Neuroscience

    Activity-dependent synapse elimination requires caspase-3 activation

    Zhou Yu, Andrian Gutu ... Erin K O'Shea
    Caspase-3 activation links synapse weakening to synapse elimination.
    1. Neuroscience

    Human brain ancestral barcodes

    Darryl Shibata
    A dynamic DNA methylation 'barcode' on the X chromosome can distinguish thousands of individual adult male neurons and may record aspects of their development.
    1. Developmental Biology
    2. Neuroscience

    A library of lineage-specific driver lines connects developing neuronal circuits to behavior in the Drosophila ventral nerve cord

    Jelly HM Soffers, Erin Beck ... Haluk Lacin
    A temporally stable and cell-type-specific genetic driver library provides the means to access and manipulate neuronal lineages in the fly nervous system during development and adulthood.
    1. Neuroscience

    Heterozygosity for neurodevelopmental disorder-associated TRIO variants yields distinct deficits in behavior, neuronal development, and synaptic transmission in mice

    Yevheniia Ishchenko, Amanda T Jeng ... Anthony J Koleske
    Heterozygosity for Trio variants leads to overlapping but distinct impacts on behavior, neuronal structure, and synaptic transmission, including newly characterized defects in presynaptic function.
    1. Neuroscience

    Neurodevelopmental Disorders: Unraveling the impact of genetic variants

    Bruce Herring
    Experiments in mice reveal how three rare mutations in a gene called TRIO can lead to different neurodevelopmental outcomes.
    Version of Record
    Insight
    1. Neuroscience

    Different roles of D1/D2 medium spiny neurons in the nucleus accumbens in pair bond formation of male mandarin voles

    Lizi Zhang, Yishan Qu ... Fa-Dao Tai
    In male mandarin voles, D1 and D2 medium spiny neurons within the nucleus accumbens shell exert distinct influences on pair bond formation.
    1. Neuroscience

    Uncertainty-modulated prediction errors in cortical microcircuits

    Katharina Anna Wilmes, Mihai A Petrovici ... Walter Senn
    A new model of how the brain's circuits compute uncertainty and use it during learning by modulating prediction error responses.
    1. Neuroscience
    2. Physics of Living Systems

    Imaging of brain electric field networks with spatially resolved EEG

    Lawrence R Frank, Vitaly L Galinsky ... Antigona Martinez
    A physics-based solution to the electroencephalography (EEG) inverse problem enables whole-brain electric field imaging with high spatial and temporal resolution using standard EEG systems.
    1. Neuroscience

    Context-dependent modulations of subthalamo-cortical synchronization during rapid reversals of movement direction in Parkinson’s disease

    Lucie Winkler, Markus Butz ... Jan Hirschmann
    Beta synchrony between motor cortex and the subthalamic nucleus is intensified when instructional cues within a continuous motor sequence become less predictable, calling for more cautious behavior.