Marco Garbelli, Stephanie Niklaus, Stephan CF Neuhauss
Loss of the glutamate transporters EAAT5b and EAAT7 disrupts wavelength-specific visual processing and UV-dependent prey detection in zebrafish, revealing their key roles in modulating light integration and behaviorally relevant vision.
Computational modeling of the memory modification process reveals biased internal states in an Alzheimer’s disease mouse model, providing a new approach for early cognitive assessment and diagnosis.
Ion channel voltage-dependence alterations can shape intrinsic homeostatic plasticity, even if operating faster than other intrinsic regulatory processes—where timescale separation would suggest its influence should be negligible.
Full-length, autoinhibited LRRK2 assembles into distinct, shorter microtubule-bound filaments via a previously unobserved N-terminal repeat interface, revealing new structural states with potential therapeutic implications.
Laura J Smithson, Juliana L Zang ... Catherine A Collins
Transcriptional responses to axonal damage are required for circuit repair, but these responses are restrained in injuries that leave spared axonal branches.
