Browse our latest Neuroscience articles

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    1. Neuroscience

    Central Nervous System: Is creatine a CNS neurotransmitter?

    Bhagaban Mallik, C Andrew Frank
    A range of experiments suggests that creatine, a molecule known for recycling ATP in muscle and brain tissue, may also function as a neurotransmitter in the central nervous system.
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    1. Neuroscience

    Adolescent neurostimulation of dopamine circuit reverses genetic deficits in frontal cortex function

    Surjeet Mastwal, Xinjian Li ... Kuan Hong Wang
    Frontal cortical circuit alterations and cognitive deficits identified in mouse genetic models are reversed by chemogenetic or optogenetic stimulation of the mesocortical dopamine circuit in an adolescent period.
    1. Cell Biology
    2. Neuroscience

    Deciphering neuronal deficit and protein profile changes in human brain organoids from patients with creatine transporter deficiency

    Léa Broca-Brisson, Rania Harati ... Aloïse Mabondzo
    Proteomic analysis of brain organoids from creatine transporter deficiency (CTD) patients enhance the understanding of CTD offering potential therapeutic targets and a robust foundation for continued research in the field.
    1. Neuroscience

    Neuromodulation of striatal D1 cells shapes BOLD fluctuations in anatomically connected thalamic and cortical regions

    Marija Markicevic, Oliver Sturman ... Nicole Wenderoth
    The structural characteristics of a circuit and its hierarchical dimensions are shown to influence regional time-series dynamics after targeted cellular-level manipulations.
    1. Neuroscience

    An observational treatment study of metacognition in anxious-depression

    Celine Ann Fox, Chi Tak Lee ... Claire M Gillan
    Improvement in levels of anxious-depression corresponds with increased confidence in performance among individuals receiving mental health treatment within a large longitudinal dataset.
    1. Cell Biology
    2. Neuroscience

    RNA-binding deficient TDP-43 drives cognitive decline in a mouse model of TDP-43 proteinopathy

    Julie C Necarsulmer, Jeremy M Simon ... Todd J Cohen
    Impairing TDP-43 RNA-binding capacity through a single acetylation-mimic mutation alters TDP-43 function and recapitulates biochemical, molecular, and behavioral features of sporadic TDP-43 proteinopathies, thus providing opportunities for new research into pathogenic mechanisms and therapeutic interventions.
    1. Neuroscience

    Sex chromosome gene expression associated with vocal learning following hormonal manipulation in female zebra finches

    Matthew H. Davenport, Ha Na Choe ... Erich D. Jarvis
    1. Neuroscience

    On the computational principles underlying human exploration

    Lior Fox, Ohad Dan, Yonatan Loewenstein
    1. Neuroscience

    Simple decoding of behavior from a complicated neural manifold

    Sean M. Perkins, John P. Cunningham ... Mark M. Churchland
    1. Genetics and Genomics
    2. Neuroscience

    Tyramine and its Amtyr1 receptor modulate attention in honey bees (Apis mellifera)

    Joseph S Latshaw, Reece E Mazade ... Brian Smith
    Genetic variation in a biogenic amines receptor underlies a means of gain control for nonassociative learning and hence an important form of attention that is the basis for tradeoffs in foraging in a social collective.