Gerbils exhibit stable, family-specific vocal dialects over weeks, suggesting vocal communication may play a key role in representing kinship in natural social groups.
Maryam Rahimi-Balaei, Shayan Amiri ... Hassan Marzban
A distinct subset of cerebellar nuclei neurons originates from a previously unrecognized germinal zone within the cerebellar primordium, independent of Atoh1 influence, highlighting new cellular origins in cerebellar development.
The important role of structural asymmetry in the functional lateralization of the same brain area provides a crucial insight into the neurobiological fundament for human brain's functional lateralization.
TIM23 core deficiency specifically impacts the oxidative phosphorylation and the mitochondrial ribosome complexes and, unexpectedly, leads to reduction of plasma membrane voltage-dependent potassium channels in neurons.
Quan-Son Eric Le, Daniel Hereford ... Jonathan P Fadok
Associative and non-associative learning mechanisms summate to produce robust and complex conditioned behavior profiles, opening new avenues to in-depth investigations of defensive responses and threat evaluation.
In astrocytes, there exists an intrinsic spatial threshold of subcellular calcium levels that triggers an astrocyte calcium surge throughout the cell, demonstrating cellular astrocyte calcium integration of time and space.
Jayanarayanan Sadanandan, Sithara Thomas ... Peeyush Kumar T
Histone deacetylase 2 (HDAC2) and polycomb repressive complex 2 (PRC2) control endothelial gene expression for BBB development and prevented Wnt/β-catenin target genes from being expressed in adult CNS ECs.
The naturally occurring biologics, FLO and HC-HA/PTX3, derived from human birth tissues, may be developed as a much-needed non-opioid therapy for post-surgical pain treatment, leveraging robust neuronal mechanisms.