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    1. Structural Biology and Molecular Biophysics

    Imaging: Nanoscopy at low light intensities shows its potential

    Travis J Gould, Joerg Bewersdorf
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    1. Structural Biology and Molecular Biophysics

    Modelling dynamics in protein crystal structures by ensemble refinement

    B Tom Burnley, Pavel V Afonine ... Piet Gros
    A combination of molecular dynamics simulations and X-ray diffraction data has been used to construct more realistic models of proteins and to provide new insights into their interactions with other proteins and biomolecules.
    1. Structural Biology and Molecular Biophysics

    Distinct gating mechanisms revealed by the structures of a multi-ligand gated K+ channel

    Chunguang Kong, Weizhong Zeng ... Youxing Jiang
    Structural and functional studies of a potassium ion channel that is opened and closed by different ligands have revealed a novel gating mechanism.
    1. Structural Biology and Molecular Biophysics
    2. Neuroscience

    Synaptic proteins promote calcium-triggered fast transition from point contact to full fusion

    Jiajie Diao, Patricia Grob ... Axel T Brunger
    A combination of advanced optical imaging and cryogenic electron microscopy has been used to explore membrane fusion in a synthetic system and provide new insights into neurotransmitter release.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    DNA Repair: Sliding to the rescue of damaged DNA

    Bryan Gibb, Eric C Greene
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    1. Structural Biology and Molecular Biophysics

    Molecular architecture of human polycomb repressive complex 2

    Claudio Ciferri, Gabriel C Lander ... Eva Nogales
    Electron microscopy has been used to produce the first three-dimensional image of the PRC2 gene-silencing complex.
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