Browse our latest Structural Biology and Molecular Biophysics articles

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    1. Structural Biology and Molecular Biophysics

    Conformational dynamics of a nicotinic receptor neurotransmitter site

    Mrityunjay Singh, Dinesh C Indurthi ... Shailendra Asthana
    Revised
    Reviewed Preprint v3
    Updated
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Isobaric crosslinking mass spectrometry technology for studying conformational and structural changes in proteins and complexes

    Jie Luo, Jeff Ranish
    A novel pair of isobaric crosslinking reagents is described, which allow relative quantification of crosslinker-modified peptides during mass spectrometry analysis for comparative structural studies of proteins and protein complexes.
    1. Structural Biology and Molecular Biophysics

    Structure of scavenger receptor SCARF1 and its interaction with lipoproteins

    Yuanyuan Wang, Fan Xu ... Yongning He
    The binding site and potential mechanism of human SCARF1 for lipoprotein recognition are identified by combining the crystal structural determination of the N-terminal fragments and biochemical and cellular assays.
    1. Structural Biology and Molecular Biophysics

    Isoleucine gate blocks K+ conduction in C-type inactivation

    Werner Treptow, Yichen Liu ... Benoit Roux
    1. Structural Biology and Molecular Biophysics

    Direct and indirect salt effects on homotypic phase separation

    Matt MacAinsh, Souvik Dey, Huan-Xiang Zhou
    All-atom molecular dynamics simulations revealed both direct and indirect salt effects and led to an amino-acid composition-based predictor for four classes of salt dependence of IDP phase separation.
    1. Structural Biology and Molecular Biophysics

    Targeted anticancer pre-vinylsulfone covalent inhibitors of carbonic anhydrase IX

    Aivaras Vaškevičius, Denis Baronas ... Daumantas Matulis
    Revised
    Reviewed Preprint v2
    Updated