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    1. Chromosomes and Gene Expression
    2. Structural Biology and Molecular Biophysics

    CTP promotes efficient ParB-dependent DNA condensation by facilitating one-dimensional diffusion from parS

    Francisco de Asis Balaguer et al.
    Single-molecule methods reveal that cytidine triphosphate promotes DNA condensation specifically at bacterial centromeres by facilitating one-dimensional diffusion of ParB from parS sites.
    1. Neuroscience
    2. Structural Biology and Molecular Biophysics

    Topography and motion of the acid-sensing ion channel intracellular domains

    Tyler Couch et al.
    1. Cell Biology
    2. Structural Biology and Molecular Biophysics

    The solubility product extends the buffering concept to heterotypic biomolecular condensates

    Aniruddha Chattaraj et al.
    The solubility product, a thermodynamic concept classically applied to poorly soluble ionic solutes, can rationalize the concentration dependence for liquid-liquid phase separation of multicomponent multivalent molecules.
    1. Computational and Systems Biology
    2. Structural Biology and Molecular Biophysics

    Development of antibacterial compounds that constrain evolutionary pathways to resistance

    Yanmin Zhang et al.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Homo-oligomerization of the human adenosine A2a receptor is driven by the intrinsically disordered C-terminus

    Khanh Dinh Quoc Nguyen et al.
    1. Chromosomes and Gene Expression
    2. Structural Biology and Molecular Biophysics

    Folding of cohesin’s coiled coil is important for Scc2/4-induced association with chromosomes

    Naomi J Petela et al.
    First evidence of cohesin folding occurring in vivo and during cohesion together with a detailed description of the structural aspects of cohesin's elbow folding through a series of novel structures.
    1. Physics of Living Systems
    2. Structural Biology and Molecular Biophysics

    Myosin-based regulation of twitch and tetanic contractions in mammalian skeletal muscle

    Cameron Hill et al.
    The physiological contraction of skeletal muscle is controlled by structural changes in the thick filaments, establishing a new paradigm for developing potential treatments for muscle weakness.
    1. Microbiology and Infectious Disease
    2. Structural Biology and Molecular Biophysics

    Structural intermediates observed only in intact Escherichia coli indicate a mechanism for TonB-dependent transport

    Thushani D Nilaweera et al.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Structure and mechanistic features of the prokaryotic minimal RNase P

    Rebecca Feyh et al.
    The novel cryo-electron microscopy structure of a bacterial protein-only RNase P illustrates how a small protein oligomerizes into a dodecameric assembly to catalyze the 5’-end maturation of tRNAs.
    1. Structural Biology and Molecular Biophysics

    A putative structural mechanism underlying the antithetic effect of homologous RND1 and RhoD GTPases in mammalian plexin regulation

    Yanyan Liu et al.
    Small Rho GTPases confer up- and downregulation in mammalian plexin signaling by differential interactions with cell membrane.
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