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    1. Structural Biology and Molecular Biophysics

    Functional Implications of the Exon 9 Splice Insert in GluK1 Kainate Receptors

    Surbhi Dhingra, Prachi M Chopade ... Janesh Kumar
    Revised
    Reviewed Preprint v3 Updated
    1. Structural Biology and Molecular Biophysics

    Water and chloride as allosteric inhibitors in WNK kinase osmosensing

    Liliana R Teixeira, Radha Akella ... Elizabeth J Goldsmith
    Revised
    Reviewed Preprint v2 Updated
    1. Structural Biology and Molecular Biophysics

    Targeted anticancer pre-vinylsulfone covalent inhibitors of carbonic anhydrase IX

    Aivaras Vaškevičius, Denis Baronas ... Daumantas Matulis
    Not yet revised
    Reviewed Preprint v1
    1. Structural Biology and Molecular Biophysics

    The Arthropoda-specific Tramtrack group BTB protein domains use previously unknown interface to form hexamers

    Artem N Bonchuk, Konstantin I Balagurov ... Pavel G Georgiev
    The cryo-EM structure of the CG6765 BTB domain and solution scattering experiments revealed a unique three-dimer hexameric assembly for the arthropod Tramtrack group BTB domains.
    1. Structural Biology and Molecular Biophysics

    Cryo-EM structures of Kv1.2 potassium channels, conducting and non-conducting

    Yangyu Wu, Yangyang Yan ... Fred J Sigworth
    Revised
    Reviewed Preprint v3 Updated
    1. Structural Biology and Molecular Biophysics

    Cryo-electron tomographic investigation of native hippocampal glutamatergic synapses

    Aya Matsui, Cathy J Spangler ... Eric Gouaux
    Revised
    Reviewed Preprint v2 Updated
    1. Structural Biology and Molecular Biophysics
    2. Cell Biology

    Molecular mapping and functional validation of GLP-1R cholesterol binding sites in pancreatic beta cells

    Affiong I Oqua, Kin Chao ... Alejandra Tomas
    Not yet revised
    Reviewed Preprint v1
    1. Structural Biology and Molecular Biophysics

    Cryo-EM structure of the CBC-ALYREF complex

    Bradley P Clarke, Alexia E Angelos ... Yi Ren
    Structural studies reveal the mechanism by which the mRNA nuclear export machinery engages with nascent transcripts through interaction with the cap binding complex.
    1. Structural Biology and Molecular Biophysics

    PPI-hotspotID for detecting protein–protein interaction hot spots from the free protein structure

    Yao Chi Chen, Karen Sargsyan ... Carmay Lim
    PPI-hotspotID, trained using an automated machine-learning framework, AutoGluon, on the largest PPI-hot spot dataset to date, detects hot spots beyond protein–protein interfaces, uncovering druggable interactions to aid design of PPI-modulating therapeutics.
    1. Structural Biology and Molecular Biophysics

    Exploring protein structural ensembles: Integration of sparse experimental data from electron paramagnetic resonance spectroscopy with molecular modeling methods

    Julia Belyaeva, Matthias Elgeti
    Complementing experimental data from EPR spectroscopy with computational modeling techniques provides access to protein structural dynamics and enables the characterization of rare protein conformations.
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