Browse our latest research

Page 16 of 1,896
    1. Neuroscience

    Modulation of human dorsal root ganglion neuron excitability by Nav1.7 inhibition

    Akie Fujita, Sooyeon Jo ... Bruce P Bean
    Inhibition of Nav1.7 sodium channels in human dorsal root ganglion neurons had larger effects to reduce threshold and upstroke velocity of action potentials compared to Nav1.8 inhibition but smaller effects to reduce repetitive firing of action potentials.
    1. Microbiology and Infectious Disease

    Mycobacterium tuberculosis suppresses protective Th17 responses during infection

    Alex Zilinskas, Amir Balakhmet ... Sarah A Stanley
    Mycobacterium tuberculosis uses its type VII secretion system and surface lipid phthiocerol dimycocerosate to suppress protective host Th17 cell responses.
    1. Immunology and Inflammation

    An IL-21R STAT hypomorph circumvents functional redundancy in germinal centre responses

    Christoph Jandl, Joanna Warren ... Cecile King
    An IL-21 receptor mutation that differentially regulates STAT1 and STAT3 activation influenced the differentiation of T follicular cells.
    1. Neuroscience

    Large language models poorly capture how word order shapes representations of sentence meaning in the human brain

    James Fodor, Carsten Murawski, Shinsuke Suzuki
    Representations from models that explicitly encode semantic roles (who did what to whom) align better with activity in language regions of the brain than representations from transformers do.
    1. Neuroscience

    Morphology and ultrastructure of pharyngeal sense organs of Drosophila larvae

    Vincent Richter, Tilman Triphan ... Andreas S Thum
    Comprehensive ultrastructural reconstruction of the Drosophila larval pharyngeal sensory system reveals the organization and diversity of its sensory structures and enables future investigations into sensory processing, feeding decisions, and behavior.
    1. Neuroscience

    Mapping the topographic organization of the human zona incerta using diffusion MRI

    Roy AM Haast, Jason Kai ... Jonathan C Lau
    Showing that the structural connectivity between the zona incerta and cortex is organized along a rostral–caudal axis.
    1. Genetics and Genomics

    Scale dependence decouple life history traits from transposable element evolution in sauropsids

    Yun Liang, Bin Zuo, Yan-Bo Sun
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Evolutionary Biology

    Design and experimental characterization of specificity-switching mutational paths of WW domains

    Ahmed Rehan, Eugenio Mauri ... Simona Cocco
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Neuroscience

    Enhancer-AAVs allow genetic access to oligodendrocytes and diverse populations of astrocytes across species

    John K Mich, Smrithi Sunil ... Boaz P Levi
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Neuroscience

    Motor unit mechanisms of speed control in mouse locomotion

    Kyle Thomas, Rhuna Gibbs ... Samuel J Sober
    Recording the spiking activity of muscle fibers at high resolution in awake, behaving mice, reveals that locomotor speed is driven by highly variable subsets of motor units.