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Rats with a history of cocaine use exhibited prolonged encoding of idiosyncratic task features in orbitofrontal cortex and a reduced ability to compress such features to identify underlying hidden states.

A velocity-nulled 3T GE-EPI fMRI method enabling 0.9-mm whole-brain imaging that suppresses vascular contamination and reliably maps layer-specific functional connectivity in human cortex.

Targeting disulfide bond formation disables multiple antibiotic resistance mechanisms and prevents cross-protection between pathogens associated with cystic fibrosis lung infections, restoring antibiotic efficacy in polymicrobial settings.

A robust and quantitative map links chromatin modification and gene expression of cells during zebrafish embryogenesis.

Computational simulations indicate that classical psychedelics could induce hallucinations by co-opting neural circuitry dedicated to sleep-dependent replay and consolidation, providing a theoretical link between seemingly disparate fields of inquiry.

PPIscreenML is a rigorously benchmarked method that uses AlphaFold2 to screen for interacting protein pairs, and it provides superior performance to other available methods.