The importance of the αC-β4 loop at the interface between the N- and C-lobes of Protein Kinase A for synergistic high-affinity binding of ATP and a pseudo substrate inhibitor.
A combination of genetic and biochemical approaches suggest that yeast Rev7 promotes DNA double-strand break repair via NHEJ and inhibits homologous recombination by blocking Mre11 nuclease and Rad50’s ATPase activities.
Differential colonization-extinction dynamics associated with species thermal preferences provide support for dispersal limitation and microclimate buffering as primary proxies by which habitat fragmentation mediates thermophilization in birds.
Multi-dendritic cibarium neurons in the fly pharynx sense mechanical force during swallowing by NOMPC, piezo, and Tmc, besides, these neurons interact with motor neurons to control food swallow.
Thomas E Forman, Marcin P Sajek ... Katherine A Fantauzzo
Upon PDGFRα signaling in mouse embryonic palatal mesenchyme cells, Srsf3 exhibits differential transcript binding, resulting in retention of the receptor in early endosomes and increased downstream PI3K-mediated Akt signaling.
