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Page 47 of 1,817
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Natural xanthones as α-Mangostin induce vasorelaxation via binding to key gating residues in the S6 domain of BK channels

    Sönke Cordeiro, Robert Patejdl ... Marianne Musinszki
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Genetics and Genomics
    2. Neuroscience

    Avoidance of hydrogen sulfide is modulated by external and internal states in Caenorhabditis elegans

    Longjun Pu, Lina Zhao ... Changchun Chen
    Mitochondrial remodeling, ROS-dependent signaling, and diverse environmental and physiological cues underlie the initiation and persistence of locomotory activity of C. elegans in toxic H2S.
    1. Chromosomes and Gene Expression

    Decapping activators Edc3 and Scd6 act redundantly with Dhh1 in post-transcriptional repression of starvation-induced pathways

    Rakesh Kumar, Fan Zhang ... Alan G Hinnebusch
    Multi-omics analyses reveal redundant functions of yeast mRNA decapping activators Scd6 and Edc3 in facilitating recruitment of helicase Dhh1 and accelerating degradation of transcripts required for respiration in glucose-replete cells.
    1. Evolutionary Biology

    Evolution of gene expression in seasonal environments

    Shuichi N Kudo, Yuka Ikezaki ... Akiko Satake
    A comparative analysis of genome-wide seasonal gene expression dynamics across four forest tree species revealed that a shared 'molecular calendar' emerges in winter, constraining gene expression evolution and potentially limiting temporal niche partitioning and species divergence in seasonal environments.
    1. Computational and Systems Biology

    Knock-down of a regulatory barcode shifts macrophage polarization destination from M1 to M2 and increases pathogen burden upon S. aureus infection

    Sathyabaarathi Ravichandran, Bharat Bhatt ... Nagasuma Chandra
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Medicine
    2. Immunology and Inflammation

    Concerted changes in the pediatric single-cell intestinal ecosystem before and after anti-TNF blockade

    Hengqi Betty Zheng, Benjamin A Doran ... Leslie S Kean
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Neuroscience

    A meta-analysis suggests that TMS targeting the hippocampal network selectively improves episodic memory

    Elena Badillo Goicoechea, Phillip F Agres ... Joel L Voss
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Convincing
    1. Neuroscience

    Visuomotor mismatch EEG responses in occipital cortex of freely moving human subjects

    Magdalena Solyga, Marek Zelechowski, Georg B Keller
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Neuroscience
    2. Computational and Systems Biology

    Alpha rhythm subharmonics underlie responsiveness to theta burst stimulation via calcium metaplasticity

    Kevin Kadak, Davide Momi ... John D Griffiths
    Not revised
    Reviewed Preprint v1
    • Useful
    • Solid
    1. Neuroscience

    Generation of biophysical neuron model parameters from recorded electrophysiological responses

    Jimin Kim, Minxian Peng ... Eli Shlizerman
    A deep generative approach learns the translation from neurons’ electrophysiological recordings to the biophysical parameters of neuron models, assisting in the development of a detailed nervous system model.
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