Tumor-suppressive protein FRMD8 inhibits breast cancer progression by regulating the level of ERα and has the possibility to be a potential target for overcoming tamoxifen treatment resistance.
Different aspects of thermal stimuli, such as speed and intensity, are detected by distinct TRP channel-based mechanisms, with TRPV1 and TRPM2 playing unique roles in warmth perception and thermal decision-making.
A subset of hippocampal place cells, which is phase-locked to fast gamma rhythms, compressively encodes information at precessing slow gamma phases and therefore predominates to theta sequence development.