Browse our latest research

Page 48 of 1,836
    1. Microbiology and Infectious Disease

    Mast cells promote pathology and susceptibility in tuberculosis

    Ananya Gupta, Vibha Taneja ... Shabaana A Khader
    Conserved mast-cell activation, marked by elevated protease expression, aligns with progressive tuberculosis across human, macaque, and murine models.
    1. Neuroscience

    Executive resources shape the impact of language predictability across the adult lifespan

    Merle Marie Schuckart, Sandra Martin ... Jonas Obleser
    Analyses of self-paced reading times reveal that linguistic prediction deteriorates under limited executive resources, with this resource sensitivity becoming markedly more pronounced with advancing age.
    1. Structural Biology and Molecular Biophysics

    Cryo-EM structure revealed a novel F-actin binding motif in a Legionella pneumophila lysine fatty acyltransferase

    Wenjie W Zeng, Garrison Komaniecki ... Yuxin Mao
    A novel F-actin-binding motif consisting of an α-helix hairpin from a Legionella pneumophila lysine fatty acyltransferase has the potential to be developed as an F-actin probe.
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    FRG1 Regulates Nonsense-Mediated mRNA Decay by Modulating UPF1 Levels

    Ananya Palo, Talina Mohapatra ... Manjusha Dixit
    Not revised
    Reviewed Preprint v1
    • Useful
    • Solid
    • Incomplete
    1. Genetics and Genomics

    The Multivariate SEM-PGS Model: Using Polygenic Scores to Investigate Cross-Trait Genetic Nurture and Assortative Mating

    Xuanyu Lyu, Jared Balbona ... Matthew C Keller
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Chromosomes and Gene Expression

    Cell cycle-resolved Hi-C reveals unexpected plasticity of A/B compartments across interphase

    Linda Choubani, Hisashi Miura ... Ichiro Hiratani
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Chromosomes and Gene Expression

    Uncoupling the TFIIH Core and Kinase Modules Leads To Misregulated RNA Polymerase II CTD Serine 5 Phosphorylation

    Gabriela Giordano, Robin Buratowski ... Stephen Buratowski
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Neuroscience
    2. Stem Cells and Regenerative Medicine

    Directed differentiation of functional corticospinal-like neurons from endogenous SOX6+/NG2+ cortical progenitors

    Abdulkadir Ozkan, Hari K Padmanabhan ... Jeffrey D Macklis
    Developmentally-based directed differentiation from cortical progenitors sets a foundation for in vitro mechanistic and therapeutic disease modeling, and toward regenerative neuronal repopulation and circuit repair.
    1. Immunology and Inflammation
    2. Neuroscience

    Microglia replacement by ER-Hoxb8 conditionally immortalized macrophages provides insight into Aicardi–Goutières syndrome neuropathology

    Kelsey M Nemec, Genevieve Uy ... F Chris Bennett
    A microglia replacement approach demonstrates that brain macrophages with patient mutations from Aicardi–Goutières syndrome, a genetic, brain predominant interferonopathy, are sufficient to drive interferon responses.