Browse our latest research

Page 48 of 1,887
    1. Neuroscience

    Multi-area activity in mouse motor cortex associated with one- and two-handed oromanual dexterity

    John M Barrett, Joshua I Glaser ... Gordon MG Shepherd
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Developmental Biology
    2. Computational and Systems Biology

    Single-cell spatial mapping reveals reproducible cell type organization and spatially-dependent gene expression in gastruloids

    Catherine G Triandafillou, Pranav Sompalle ... Arjun Raj
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Exceptional
    1. Neuroscience

    CellCover defines marker gene panels capturing developmental progression in neocortical neural stem cell identity

    Lanlan Ji, An Wang ... Donald Geman
    In contrast to differential expression-based methods, which evaluate and select individual marker genes, CellCover identifies panels of genes that function together to define cell types.
    1. Neuroscience

    Behavioral signatures of post-decisional attention in preferential choice

    Ariel Zylberberg, Ian Krajbich, Michael N Shadlen
    Gaze patterns during value-based choice may reflect post-decision processes rather than a direct causal influence of attention on preference formation.
    1. Medicine

    Magnesium isoglycyrrhizinate alleviates alcohol-associated liver disease through targeting HSD11B1

    Lu Xiao, Lu Li ... Jia Xiao
    MgIG directly targets HSD11B1 to alleviate alcohol-associated liver disease by suppressing the HSD11B1–SREBP2–IDI1 pathway, thereby reducing hepatic steatosis, inflammation, and apoptosis.
    1. Neuroscience

    Excitatory cholecystokinin neurons in the CA3 area regulate the navigation learning and neuroplasticity

    Fengwen Huang, Abdul Baset, Stephen Temitayo Bello
    Cholecystokinin release from CA3 inputs to CA1 links local excitatory circuitry to hippocampal plasticity and spatial memory.
    1. Genetics and Genomics
    2. Cancer Biology

    Multimodal single-cell analyses reveal distinct fusion-regulated transcriptional programs in Ewing sarcoma

    Olivia G Waltner, April A Apfelbaum ... Scott N Furlan
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Compelling
    1. Cell Biology
    2. Neuroscience

    Stable excitatory-inhibitory synapse balance despite dynamic turnover

    Krassimira A Garbett, James P Allen ... Richard C Sando
    Long-term live imaging and tracking approaches reveal a coordination between excitatory and inhibitory synapse assembly, despite continual spatiotemporal dynamics.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Reprogramming of host energy metabolism mediated by the TNF-iNOS-HIF-1α axis plays a key role in host resistance to Plasmodium infection

    Kely Catarine Matteucci, Nathalia PS Leite ... Ricardo T Gazzinelli
    TNF-driven metabolic reprogramming enhances glucose utilization in monocytes through inducible nitric oxide synthase (iNOS) and hypoxia-inducible factor 1α (HIF-1α), promoting parasite control and host resistance during Plasmodium infection.