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    1. Cancer Biology
    2. Computational and Systems Biology

    BEHAV3D Tumor Profiler to map heterogeneous cancer cell behavior in the tumor microenvironment

    Emilio Rios-Jimenez, Anoek Zomer ... Maria Alieva
    BEHAV3D Tumor Profiler enables researchers without computational expertise to uncover heterogeneous cell behaviors and explore their relationships with microenvironmental features in intravital microscopy data.
    1. Ecology
    2. Physics of Living Systems

    The dominant–egalitarian transition in species-rich communities

    David A Kessler, Nadav M Shnerb
    A model of a species-rich neutral ecosystem, perturbed by environmental noise impacting each species differently, predicts that for large noise the community is dominated by a few species, while for weaker noise it is more egalitarian, with many significant species.
    1. Chromosomes and Gene Expression
    2. Cancer Biology

    Degradation of LMO2 in T cell leukaemia results in collateral breakdown of transcription complex partners and causes LMO2-dependent apoptosis

    Naphannop Sereesongsaeng, Carole JR Bataille ... Terry H Rabbitts
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Neuroscience

    Foveated metamers of the early visual system

    William F Broderick, Gizem Rufo ... Eero P Simoncelli
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Genetics and Genomics

    MerQuaCo: a computational tool for quality control in image-based spatial transcriptomics

    Naomi Martin, Paul Olsen ... Jack Waters
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Compelling
    1. Neuroscience

    Toward Robust Neuroanatomical Normative Models: Influence of Sample Size and Covariates Distributions

    Camille Elleaume, Bruno Hebling Vieira ... the Australian Imaging Biomarkers and Lifestyle flagship study of ageing
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Neuroscience

    Adult-neurogenesis allows for representational stability and flexibility in early olfactory system

    Zhen Chen, Krishnan Padmanabhan
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Chromosomes and Gene Expression
    2. Developmental Biology

    HIF1A-mediated pathways promote euploid cell survival in chromosomally mosaic embryos

    Estefania Sanchez-Vasquez, Marianne E Bronner, Magdalena Zernicka-Goetz
    Aneuploid mosaic mouse embryos require hypoxia for survival, and understanding these pathways may inform new strategies to support embryo viability.
    1. Neuroscience

    Homeostatic synaptic plasticity of miniature excitatory postsynaptic currents in mouse cortical cultures requires neuronal Rab3a

    Andrew G Koesters, Mark M Rich, Kathrin Engisch
    The first demonstration that a protein thought to function presynaptically (Rab3a) is required for homeostatic, activity-dependent synaptic plasticity of quantal size in central neurons.
    1. Computational and Systems Biology

    A network regularized linear model to infer spatial expression pattern for single cell

    Chaohao Gu, Hu Chen, Zhandong Liu
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Convincing
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