Browse our latest research

Page 48 of 1,862
    1. Computational and Systems Biology
    2. Physics of Living Systems

    A Coma Pattern-Based Autofocusing Method Resolves Bacterial Cold Shock Response at Single-Cell Level

    Sihong Li, Zhixin Ma ... Shuqiang Huang
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Chromosomes and Gene Expression
    2. Computational and Systems Biology

    Evidence of off-target probe binding affecting 10x Genomics Xenium gene panels compromise accuracy of spatial transcriptomic profiling

    Caleb Hallinan, Hyun Joo Ji ... Jean Fan
    Computational assessment identifies probe binding errors in a widely used commercial platform for spatial transcriptomics.
    Version of Record
    Short Report
    • Valuable
    • Convincing
    1. Genetics and Genomics

    Adapting clinical chemistry plasma as a source for liquid biopsies

    Spencer C Ding, Jingru Yu ... Wei Gu
    Residual plasma from rapid routine clinical chemistry tubes enables cell-free DNA NGS-based analysis, providing an untapped, scalable, and accessible resource without specialized collection workflows.
    1. Cancer Biology
    2. Microbiology and Infectious Disease

    RadD from Fusobacterium nucleatum engages NKp46 to promote antitumor cytotoxicity

    Ahmed Rishiq, Johanna Galaski ... Ofer Mandelboim
    RadD recognition by NKp46 converts Fusobacterium nucleatum from an immune-evasive pathogen into a trigger of natural killer cell-mediated tumor control in a context-dependent manner.
    1. Neuroscience

    Autonomic reflex plasticity associates with time-dependent SUDEP susceptibility in a murine model with hyperactive stress circuits

    Sandy E Saunders, Kaylie E Dow ... Carie R Boychuk
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    • Incomplete
    1. Neuroscience
    2. Computational and Systems Biology

    Parallel Wires: A Conserved Principle of Contralateral-Ipsilateral Segregation in the Visual Corpus Callosum

    Jiaowen Wang, Yanming Wang ... Xiaoxiao Wang
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Genetics and Genomics

    Identification of a somatic H3K23me3 methyltransferase SET-19 in C. elegans

    Mingjing Xu, Zixue Fan ... Xuezhu Feng
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Compelling
    1. Neuroscience

    On-demand seizures facilitate rapid screening of therapeutics for epilepsy

    Yuzhang Chen, Brian Litt ... Hajime Takano
    An on-demand seizure model in chronically epileptic mice integrates reliability and etiological relevance, providing a mechanistically grounded, efficient platform for evaluating pharmacological interventions.
    1. Microbiology and Infectious Disease

    Bivalent mRNA booster encoding virus-like particles elicits potent polyclass receptor-binding domain antibodies in pre-vaccinated mice

    Chengcheng Fan, Alexander A Cohen ... Magnus AG Hoffmann
    Bivalent EABR mRNA boosters broaden neutralizing responses to Omicron subvariants by promoting diverse receptor-binding domain epitope targeting, although antibody responses remain partially shaped by immune imprinting from prior vaccination.