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Molecular, genetic, and behavioral assays in mice establish a new role for Hox proteins in the final steps of spinal motor neuron development.

Retinoic acid signaling from Muller glia is necessary for cone photoreceptor survival in the peripheral retina and is sufficient to promote cone survival in the central retina during retinal degeneration.

A neuroprotective role mediated by Strip1 maintains retinal ganglion cells during development, which ensures proper positioning of inner retinal neurons and preserves the laminar architecture of the inner retina.

Trans genetic variation in TdT and Artemis loci impacts V(D)J recombination probabilities.

A Traditional Chinese Medicine botanical drug exerts a competitive antagonism on the cAMP-induced modulation of sinoatrial node pacemaker channels and this functional inhibition reduces the slope of the diastolic depolarization hence spontaneous cell automaticity.

Mindbomb1 acts independently of it well-known role in Notch signalling to control the endocytic internalization of the Wnt co-receptor Ryk and thereby modulate the activity of the Planar Cell Polarity pathway that governs morphogenetic movements during embryonic development.

The upregulation of TLN1 contributes to the metastasis of triple-negative breast cancer (TNBC), and a small-molecule C67399 was screened for blocking TLN1 and integrin β1 may hold promise for the treatment of TNBC.

Shank promotes functional coupling between CaV1 calcium channels and BK potassium channels.

Responses to odour mixtures are more discriminable in awake, behaving mice due to a combination of dampened responses keeping responses in the linear range and pattern decorrelation, with these two mechanisms operating on different timescales.

All steps of a viroid-like replication cycle can be catalyzed by RNA alone.