1. Genetics and Genomics
  2. Neuroscience
Download icon

Behavioral Inheritance: When mothers leave their mark

  1. Raquel Barajas-Azpeleta
  2. Kausik Si  Is a corresponding author
  1. Stowers Institute for Medical Research, United States
Insight
Cite this article as: eLife 2019;8:e48899 doi: 10.7554/eLife.48899
1 figure

Figures

Transgenerational inheritance of egg-laying preference in flies.

In normal conditions (left panel) Drosophila females prefer to lay their eggs in food that does not contain ethanol. However, when they cohabit with endoparasitoid wasps, they start to prefer to lay their eggs in food that contains ethanol, as this protects against the parasite. This switch in behavior is accompanied by decreased expression of neuropeptide F (NPF) in the brain and germcell apoptosis (middle panel). The adults hatched from these eggs (right panel) also prefer to lay eggs in food with ethanol and have reduced NPF levels in the brain, even though they have never been exposed to the wasps. The behavioral switch is maintained for up to five generations (not shown). F1: First filial generation. F2: Second filial generation.

Download links

A two-part list of links to download the article, or parts of the article, in various formats.

Downloads (link to download the article as PDF)

Download citations (links to download the citations from this article in formats compatible with various reference manager tools)

Open citations (links to open the citations from this article in various online reference manager services)