Memory: A divalent boost from magnesium

Enhanced levels of dietary magnesium improve long-term memory in fruit flies.
1 figure


Elevated levels of magnesium (Mg++) can enhance long-term memory performance in the fruit fly.

Fruit flies were fed a diet supplemented with either 1 mM (the control group) or 80 mM magnesium chloride (MgCl2) for four days, and then trained to associate food with an odor (known as appetitive olfactory conditioning). Memory was tested by allowing the flies to choose between rewarded (pink) and unrewarded (green) odors. Immediate memory (tested seconds after training) is similar in both groups of flies. However, flies fed a high-magnesium diet do not exhibit the normal decline in memory observed at 24 hours after training. Performance = {[flies choosing rewarded odor]-[flies choosing unrewarded odor]}/[flies choosing either odor].

Download links

A two-part list of links to download the article, or parts of the article, in various formats.

Downloads (link to download the article as PDF)

Open citations (links to open the citations from this article in various online reference manager services)

Cite this article (links to download the citations from this article in formats compatible with various reference manager tools)

  1. Willem J Laursen
  2. Paul A Garrity
Memory: A divalent boost from magnesium
eLife 10:e65359.