Haley N Mendoza-Romero, Jessica E Biddinger ... Richard Simerly
Hypothalamic microglia play an essential role in mediating changes to feeding circuitry caused by exposure to maternal HFD that may contribute to developmental programming of metabolic phenotype.
The blueprint and narrative of shape formation during early development can be objectively observed by quantifying and analyzing whole-embryo dynamics.
Individuals with a late circadian rhythm show the same deficits in motivational decision-making as those with neuropsychiatric symptoms, but only when tested in the morning.
A longitudinal, deep learning approach reveals challenges and opportunities in establishing brain age as an effective metric of aging, with particular consideration given to underrepresented populations in Asia.
Functional neural circuit dissection identifies sensorimotor responses to noxious cold in Drosophila larvae revealing complex mechanisms by which nervous systems sense and respond to cold.
Separating alpha oscillations from broadband activity reveals that alpha suppression in the human visual cortex is highly localized, and modulates cortical state in a manner consistent with exogenous spatial attention.
Hannes P Saal, Ingvars Birznieks, Roland S Johansson
Fingertip tactile neurons collectively encode the skin's viscoelastic state alongside current touch, potentially enabling the brain to better interpret forces during manipulation.
Parham Mostame, Jonathan Wirsich ... Sepideh Sadaghiani
Parallel connectome trajectories unfold asynchronously across timescales, sustaining a multiplex of functionally distinct brain networks operating at different speeds.
BCAS2 directly binds to the Armadillo repeats 9–12 of β-catenin via the coiled-coil domains, sequestering β-catenin within the nucleus and thereby promoting Wnt signaling during primitive hematopoiesis.