Browse our Research Articles

The mean, variance, and autocorrelation of glucose dynamics are independently associated with coronary plaque vulnerability.

BK and Ca_V1.3 channels interact early during biogenesis, assembling intracellularly before membrane localization, indicating coordinated processes for functional coupling.

Bioinformatics, RNA-protein interactions, and HuR-based functional studies demonstrated that the rs13900T allele modulates CCL2 transcript levels, providing a functional link between the CCL2 rs1024611G-rs13900T haplotype and disease susceptibility/progression.

CDK2-mediated TBK1 degradation via Dtx4 represents a previously unrecognized regulatory mechanism that modulates antiviral immunity in fish.

A context-driven memory model simulates a wide range of characteristics of waking and sleeping hippocampal replay, providing a new account of how and why replay occurs.

A new CRISPR-based approach for tuning gene expression up and down allowed identification of how other genes' expression responds to changes of transcription factors.

Exosome-associated THSD7A is identified as a key trigger of filopodia formation in cancer cells and neurons, revealing a novel pathway with implications for metastasis, neuronal connectivity, and other filopodia-dependent processes.

Prefoldin 5 stabilises neuronal microtubules and suppresses Tau-mediated neurotoxicity, offering a potential therapeutic target for tauopathies.

Cryo-EM structures of human aquaporin AQP2 bound to the anti-trypanosomal drugs pentamidine and melarsoprol identify the molecular mechanism for drug-resistant sleeping sickness.

Synthetic ribbon-type active zones are reconstituted in cultured cells using a minimal set of proteins that partially mimic structural and functional features of cochlear inner hair cell active zones.