Browse our Research Articles

Page 10 of 1,399
    1. Neuroscience

    Fingertip viscoelasticity enables human tactile neurons to encode loading history alongside current force

    Hannes P Saal, Ingvars Birznieks, Roland S Johansson
    Fingertip tactile neurons collectively encode the skin's viscoelastic state alongside current touch, potentially enabling the brain to better interpret forces during manipulation.
    1. Neuroscience

    A multiplex of connectome trajectories enables several connectivity patterns in parallel

    Parham Mostame, Jonathan Wirsich ... Sepideh Sadaghiani
    Parallel connectome trajectories unfold asynchronously across timescales, sustaining a multiplex of functionally distinct brain networks operating at different speeds.
    1. Developmental Biology

    BCAS2 promotes primitive hematopoiesis by sequestering β-catenin within the nucleus

    Guozhu Ning, Yu Lin ... Qiang Wang
    BCAS2 directly binds to the Armadillo repeats 9–12 of β-catenin via the coiled-coil domains, sequestering β-catenin within the nucleus and thereby promoting Wnt signaling during primitive hematopoiesis.
    1. Computational and Systems Biology

    A mathematical model that predicts human biological age from physiological traits identifies environmental and genetic factors that influence aging

    Sergiy Libert, Alex Chekholko, Cynthia Kenyon
    A model was developed to predict human biological age from physiological traits, enabling the prediction of future health and mortality and the identification of genetic loci that influence aging.
    1. Neuroscience

    Embedding stochastic dynamics of the environment in spontaneous activity by prediction-based plasticity

    Toshitake Asabuki, Claudia Clopath
    A computational model shows how synaptic plasticity shapes spontaneous activity to encode the transition statistics of sensory experience.
    1. Neuroscience

    Mapping vascular network architecture in primate brain using ferumoxytol-weighted laminar MRI

    Joonas A Autio, Ikko Kimura ... Takuya Hayashi
    Ferumoxytol-enhanced MRI enables high-resolution, laminar mapping of cerebral blood volume in the primate brain, validating core neurovascular features and advancing noninvasive tools for neurometabolic imaging.
    1. Microbiology and Infectious Disease

    Caffeic acid phenethyl ester protects Clostridioides difficile infection by toxin inhibition and microbiota modulation

    Yan Guo, Yong Zhang ... Jiazhang Qiu
    Caffeic acid phenethyl ester treats Clostridioides difficile infection by neutralizing Clostridioides difficile toxin B and altering the gut microbiota and metabolites.
    1. Cell Biology
    2. Genetics and Genomics

    Kinesin-2 autoinhibition requires elbow phosphorylation

    Guanghan Chen, Zhengyang Guo ... Guangshuo Ou
    Phosphorylation of the kinesin-2 motor protein’s elbow region by NEKL-3 kinase maintains autoinhibition, enabling its transport to cilia for sensory function.
    1. Epidemiology and Global Health

    A sex-specific Mendelian randomization-phenome-wide association study of body mass index

    Zhu Liduzi Jiesisibieke, Io Ieong Chan ... C Mary Schooling
    Higher body mass index has a wide range of harmful health effects, which sometimes appear to be more pronounced in men, suggesting that higher BMI may be one of the factors contributing to differences in lifespan between men and women.