Browse our Research Articles

Page 10 of 1,430
    1. Neuroscience

    Oxytocin restores context-specific hyperaltruistic preference

    Hong Zhang, Yinmei Ni, Jian Li
    Oxytocin facilitates hyperaltruism by promoting harm-framing in the moral decision-making task.
    1. Neuroscience

    Rab10 inactivation promotes AMPAR trafficking and spine enlargement during long-term potentiation

    Jie Wang, Jun Nishiyama ... Ryohei Yasuda
    Rab10 and Rab4 bidirectionally regulate AMPA receptor trafficking and spine structural plasticity during long-term potentiation by exhibiting opposing and temporally distinct activity patterns in stimulated dendritic spines.
    1. Structural Biology and Molecular Biophysics

    Multiphase separation in postsynaptic density regulated by membrane geometry via interaction valency and volume

    Risa Yamada, Giovanni B Brandani, Shoji Takada
    Membrane geometry switches protein condensate organization of postsynaptic density proteins by reducing crowding effects while maintaining specific binding, allowing targeted interactions to dominate over size-based exclusion.
    1. Neuroscience

    Hierarchical encoding of natural sound mixtures in ferret auditory cortex

    Agnès Landemard, Célian Bimbard, Yves Boubenec
    To parse foreground and background sounds, the auditory cortex of humans and ferrets share a similar hierarchical organization, but the underlying computational mechanisms are fundamentally different.
    1. Microbiology and Infectious Disease

    The increase in cell volume and nuclear number of the koji-fungus Aspergillus oryzae contributes to its high enzyme productivity

    Ayaka Itani, Haruto Motomura ... Norio Takeshita
    More nuclei and cell volume, more enzymes in koji-fungus Aspergillus oryzae.
    1. Cell Biology
    2. Developmental Biology

    Sulfation affects apical extracellular matrix organization during development of the Drosophila embryonic salivary gland tube

    J Luke Woodward, Jeffrey Matthew ... SeYeon Chung
    Sulfation is required for organizing the apical extracellular matrix during tubular organ formation.
    1. Computational and Systems Biology

    Identification of type 2 diabetes- and obesity-associated human β-cells using deep transfer learning

    Gitanjali Roy, Rameesha Syed ... Michael A Kalwat
    Deep transfer learning methodologies reveal hidden heterogeneity in β-cells driven by type 2 diabetes and obesity.
    1. Microbiology and Infectious Disease

    A SHERLOCK toolbox for eco-epidemiological surveillance of African trypanosomes in domestic pigs from Western Africa

    Roger Eloiflin, Elena Pérez-Antón ... Brice Rotureau
    A novel array of CRISPR-based SHERLOCK tests for RNA detection was developed for eco-epidemiological surveillance of human and animal African trypanosomes from Western Africa with domestic pigs as sentinels.
    1. Cell Biology
    2. Neuroscience

    Maintenance of neuronal TDP-43 expression requires axonal lysosome transport

    Veronica H Ryan, Sydney Lawton ... Michael Emmerson Ward
    Protein, but not mRNA, levels of neurodegenerative disease-associated protein TDP-43 are decreased upon knockdown of BORC, a complex that is required for the anterograde transport of lysosomes.
    1. Neuroscience

    Human single-neuron activity is modulated by intracranial theta burst stimulation of the basolateral amygdala

    Justin M Campbell, Rhiannon L Cowan ... Jon Timothy Willie
    Firing rate analyses revealed neurons throughout the hippocampus, amygdala, orbitofrontal cortex, and anterior cingulate cortex in humans that exhibited heterogeneous responses to intracranial theta burst stimulation of the human brain.