Browse our Research Articles

Page 10 of 1,438
    1. Neuroscience

    Spatiotemporal brain complexity quantifies consciousness outside of perturbation paradigms

    Martin Breyton, Jan Fousek ... Viktor Jirsa
    Brain fluidity metrics provide an accessible and reliable marker of consciousness, offering a practical alternative to perturbational complexity for clinical and research applications.
    1. Stem Cells and Regenerative Medicine

    Chromatin activity of IκBα mediates the exit from naïve pluripotency

    Luis G Palma, Daniel Alvarez-Villanueva ... Anna Bigas
    The development of novel separation-of-function mutants has uncovered non-canonical chromatin roles of IκBα in regulating mouse embryonic stem cell pluripotency and differentiation, independently of the classical NF-κB pathway.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    IFIT1 is rapidly evolving and exhibits disparate antiviral activities across 11 mammalian orders

    Matthew B McDougal, Ian N Boys ... John W Schoggins
    Evolutionary changes in RNA binding and antiviral activity result in diverse IFIT1 functions across mammals, even among closely related species.
    1. Stem Cells and Regenerative Medicine

    Stabilisation of HIF signalling in the mouse epicardium extends embryonic potential and neonatal heart regeneration

    Elisabetta Gamen, Eleanor L Price ... Paul R Riley
    Extending hypoxia signalling after birth extends the window of heart regeneration.
    1. Neuroscience

    Blood pressure variability compromises vascular function in middle-aged mice

    Perenkita J Mendiola, Philip O'Herron ... Jessica A Filosa
    Chronic variations in blood pressure compromise brain health.
    1. Neuroscience

    Sequential temporal anticipation characterized by neural power modulation and in recurrent neural networks

    Xiangbin Teng, Ru-Yuan Zhang
    Predicting key future moments requires ignoring most irrelevant time, and alpha and beta power modulations encode sequential temporal landmarks via a gain-control mechanism that suppresses these irrelevant periods.
    1. Neuroscience

    Asymmetric cortical projections to striatal direct and indirect pathways distinctly control actions

    Jason R Klug, Xunyi Yan ... Xin Jin
    A modified rabies-based circuit-mapping strategy combined with physiology, optogenetics, and behavior identifies asymmetric corticostriatal subcircuits that exert distinct control over actions.
    1. Computational and Systems Biology

    Twist is the key to the gating of mechanosensitive ion channel NOMPC

    Jingze Duan, Chen Song
    Rotation of the transient receptor potential (TRP) domain appears to be a universal mechanism for gating of the TRP channel family, including the mechanosensitive ion channel NOMPC.
    1. Neuroscience

    3D directional tuning in the orofacial sensorimotor cortex during natural feeding and drinking

    Victoria B Hosack, Fritzie Arce-McShane
    There is significant information about continuous 3D tongue direction contained in the primate orofacial sensorimotor cortex during untrained tasks, and alterations to tongue kinematics and directional tuning with temporarily induced sensory loss.
    1. Microbiology and Infectious Disease

    The capsule and genetic background, rather than specific individual loci, strongly influence in vitro pneumococcal growth kinetics

    Chrispin Chaguza, Daan W Arends ... Amelieke JH Cremers
    The pneumococcal capsular serotype and genetic background, as well as a combination of genomic loci, influence intrinsic pneumococcal growth kinetics, which may have implications for pneumococcal disease pathogenesis.