Browse our Research Articles

Computational modelling suggests that the segmentation clock and the morphogenesis of the pre-somitic mesoderm exhibit developmental modularity, enabling the independent evolution of these processes and possibly contributing to the high evolvability of vertebrate segment number.

Behavioral and functional analyses revealed that UBR-1 deficiency in Caenorhabditis elegans disrupts glutamate signaling and confers ivermectin resistance.

Infralimbic inhibitory parvalbumin neurons play a counterintuitive role in supporting flexible behavior in the face of threat.

Crystallography, molecular dynamics simulations, and biochemical analyses of Calvin-Benson-Bassham sedoheptulose-1,7-bisphosphatase (SBPase) from the microalga Chlamydomonas reinhardtii identify a redox module that controls oligomeric states for the activation of the enzyme.

The peripherally restricted opioid receptor antagonist naloxone methiodide reverses fentanyl-induced respiratory depression without causing aversive behaviors that are observed after naloxone.

Meta-analysis reveals there is no evidence that variation in clutch size in birds is driven by the reproduction–survival trade-off.

The central nitrogen-metabolite 2-oxoglutarate directly promotes glutamine synthetase activity by inducing its dodecameric assembly and priming the active sites, representing a novel mechanism of regulation.

The genome-wide transcriptional regulatory network in Pseudomonas syringae demonstrates the regulatory diversity and functional pathways.

Fitness defects arising from deletion of the gene encoding the bacterial equivalent of actin (mreB) are readily compensated by mutations affecting cell wall synthesis.

Genetically diverse Mycobacterium tuberculosis complex strains induce a gamut of human granulomatous responses in vitro, with a role for IL-1β in aggregate formation.