Browse our Research Articles

Drosophila female germline tumors mutant for bam or bgcn mimic the stem cell niche to inhibit the differentiation of neighboring wild-type germline stem cells.

Replication origins in Trypanosoma brucei integrate multiple features previously described individually in opisthokonts, revealing a unified structural topology built from strand-specific nucleotide composition, G‑quadruplex enrichment, and distinctive nucleosome patterns.

Neural reward signals following effort are amplified for self-benefiting outcomes but attenuated for other-benefiting outcomes, contingent upon reward magnitude and individual effort sensitivity.

A newly developed chemo-immunological strategy enabled detection of acetoacetate-mediated lysine acetoacetylation, identified the associated regulatory enzymes, and revealed its distinct biological functions and physiological significance.

Meta-analysis indicates that network-targeted non-invasive brain stimulation consistently enhances memory function supported by the hippocampal network, thus providing robust evidence that specific memory abilities rely on specific modifiable brain networks.

Selective engagement of suprapyramidal dentate gyrus neurons during a high-demand pattern separation task reveals blade-specific circuit engagement for enhancing mnemonic discrimination.

Progressive DNA polymerase kappa relocalization in aging neurons associates with increased DNA damage and identifies a novel cell type- and activity-dependent role in neuronal genome maintenance.

Inhibiting locus coeruleus input to the medial prefrontal cortex in mice impaired task performance, affected the tuning of single cortical neurons and disrupted population dynamics and encoding capacity during attentional switching.

A biologically plausible reinforcement learning model that integrates associative memory and hippocampal remapping explains context-dependent flexible behavior, neural dynamics, and psychosis-related symptoms.

Recurrent neural network models trained on a novel motor skill exhibit a persistent shift in preparatory activity that enables faster relearning, without cognitive or contextual cues.