Browse our Research Articles

Page 11 of 1,398
    1. Cell Biology

    Clearance of protein aggregates during cell division

    Shoukang Du, Yuhan Wang ... Ting Gang Chew
    ER aggregates confined in the nucleus are cleared via ER reorganization when cells progress through mitosis and cytokinesis.
    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    A general mechanism for initiating the bacterial general stress response

    Rishika Baral, Kristin Ho ... Niels Bradshaw
    A coiled-coil-based transduction mechanism is identified for a serine/threonine phosphatase that controls a bacterial stress response, suggesting that phosphatases are part of a modularly exchangeable toolkit for bacterial signaling.
    1. Neuroscience

    Different roles of D1/D2 medium spiny neurons in the nucleus accumbens in pair bond formation of male mandarin voles

    Lizi Zhang, Yishan Qu ... Fa-Dao Tai
    In male mandarin voles, D1 and D2 medium spiny neurons within the nucleus accumbens shell exert distinct influences on pair bond formation.
    1. Evolutionary Biology
    2. Genetics and Genomics

    Upstream open reading frames buffer translational variability during Drosophila evolution and development

    Yuanqiang Sun, Yuange Duan ... Jian Lu
    Upstream open reading frames (uORFs) function as regulatory elements that buffer translation variability, stabilizing protein expression across animal developmental stages and evolutionary timescales.
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Deep sequencing of yeast and mouse tRNAs and tRNA fragments using OTTR

    Hans Tobias Gustafsson, Lucas Ferguson ... Oliver J Rando
    A recently developed RNA cloning protocol efficiently captures both intact and fragmented tRNAs.
    1. Neuroscience

    Hierarchy between forelimb premotor and primary motor cortices and its manifestation in their firing patterns

    Akiko Saiki-Ishikawa, Mark Agrios ... Andrew Miri
    During reaching in mice, forelimb premotor cortex has a stronger influence on primary motor cortex than vice versa, but several functional connectivity measures fail to reflect this asymmetry.
    1. Microbiology and Infectious Disease

    Chalkophore-mediated respiratory oxidase flexibility controls M. tuberculosis virulence

    John A Buglino, Yaprak Ozakman ... Michael S Glickman
    M. tuberculosis produces a copper binding diisonitrile chalkophore to maintain the copper-dependent respiratory oxidase during infection, identifying a pathogen strategy that defends oxidative phosphorylation against host attack.
    1. Neuroscience

    Uncertainty-modulated prediction errors in cortical microcircuits

    Katharina Anna Wilmes, Mihai A Petrovici ... Walter Senn
    A new model of how the brain's circuits compute uncertainty and use it during learning by modulating prediction error responses.
    1. Neuroscience
    2. Physics of Living Systems

    Imaging of brain electric field networks with spatially resolved EEG

    Lawrence R Frank, Vitaly L Galinsky ... Antigona Martinez
    A physics-based solution to the electroencephalography (EEG) inverse problem enables whole-brain electric field imaging with high spatial and temporal resolution using standard EEG systems.
    1. Computational and Systems Biology

    Dynamical mechanisms of growth-feedback effects on adaptive gene circuits

    Ling-Wei Kong, Wenjia Shi ... Ying-Cheng Lai
    Systematic simulations reveal how growth feedback undermines the stability of adaptive gene circuits in a topology-dependent manner.