Browse our Research Articles

Page 11 of 1,499
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Genome reorganization and its functional impact during breast cancer progression

    Kathleen S Metz Reed, Andrew Fritz ... Tom Misteli
    Genome-wide maps of chromatin structure in a cell-based model of breast cancer reveal chromatin reorganization accompanied by changes in transcription and epigenetic marks.
    1. Neuroscience

    Linear and categorical coding units in the mouse gustatory cortex drive population dynamics and behavior in taste decision-making

    Liam Lang, Camelia Yuejiao Zheng ... Alfredo Fontanini
    Linear or categorical activity from neurons in the gustatory cortex is necessary for network dynamics and performance.
    1. Evolutionary Biology

    Are interphylum spiralian relationships resolvable?

    Ana Serra Silva, Maximilian J Telford
    Analyses of two independent phylogenomic datasets suggest an explosive radiation at the origin of Spiralia, with implications for understanding the group's evolutionary history.
    1. Neuroscience

    Exposure to false cardiac feedback alters pain perception and anticipatory cardiac frequency

    Eleonora Parrotta, Patric Bach ... Francesca Ferri
    Interoceptive predictions can bias both the subjective experience of pain and physiological preparation.
    1. Cancer Biology
    2. Chromosomes and Gene Expression

    The DBD-α4 helix of EWSR1::FLI1 is required for GGAA microsatellite binding that underlies genome regulation in Ewing sarcoma

    Ariunaa Bayanjargal, Cenny Taslim ... Emily Rose Theisen
    A discrete helix in the fusion oncoprotein DNA binding domain shifts binding preferences toward long and dense GGAA repeats, which promotes transcriptional hub formation and drives EWSR1::FLI1-mediated gene regulation.
    1. Biochemistry and Chemical Biology

    Nuclear CK1δ as a critical determinant of PER:CRY complex dynamics and circadian period

    Fidel Emmanuel Serrano, Daniela Marzoll ... Michael Brunner
    Repressive PER2:CRY1:CK1δ complexes assembling in the cytosol enter the nucleus, where PER2 hyperphosphorylation eventually disrupts the complex, causing PER2 to relocalize to the cytoplasm, allowing nuclear accumulation of CRY1.
    1. Neuroscience

    Disrupted hippocampal theta-gamma coupling and spike-field coherence following experimental traumatic brain injury

    Christopher D Adam, Ehsan Mirzakhalili ... John A Wolf
    Experimental TBI results in distinct patterns of network-level pathophysiology in the hippocampus that may contribute to TBI-associated cognitive deficits.
    1. Microbiology and Infectious Disease

    Starvation of the bacterium Vibrio atlanticus induces simultaneous attacks on the dinoflagellate Alexandrium pacificum

    Jean-Luc Rolland, Estelle Masseret ... Raphael Lami
    Vibrio bacteria act as predators of ecologically significant algae that contribute to harmful blooms.
    1. Cell Biology
    2. Chromosomes and Gene Expression

    Contractile perinuclear actomyosin network promotes peripheral and polar chromosome interaction with the mitotic spindle

    Nooshin Sheidaei, John K Eykelenboom ... Tomoyuki U Tanaka
    An actomyosin network (PANEM) forms around the nucleus in prophase, and its contraction repositions peripheral and polar chromosomes to facilitate their interaction with the mitotic spindle, ensuring their correct segregation.
    1. Neuroscience

    Tactile localization of the breast, areola, and nipple

    Katie H Long, Emily E Fitzgerald ... Charles M Greenspon
    The breast, despite its importance in sexual and affective touch, exhibits poor tactile localization and demonstrates a relationship between size and innervation density.