Browse our Short Reports

Page 46 of 61
    1. Neuroscience

    Visual attention is available at a task-relevant location rapidly after a saccade

    Tao Yao, Madhura Ketkar ... B Suresh Krishna
    Spatial attention and saccadic processing co-ordinate to ensure that attention is available at a task-relevant location soon after the beginning of each eye fixation.
    1. Neuroscience

    Chronic social isolation reduces 5-HT neuronal activity via upregulated SK3 calcium-activated potassium channels

    Derya Sargin, David K Oliver, Evelyn K Lambe
    Serotonin neurons in chronically isolated mice become less responsive to excitatory stimulation, but inhibiting a distinctive calcium-activated potassium channel can restore both neuronal activity and behavior.
    1. Neuroscience

    Rotating waves during human sleep spindles organize global patterns of activity that repeat precisely through the night

    Lyle Muller, Giovanni Piantoni ... Terrence J Sejnowski
    A phase-based analysis reveals wave-like spatiotemporal organization of the human sleep spindle, a brain oscillation critical to sleep-dependent memory consolidation, and elucidates its role in coordinating activity of neural networks distributed across the cortex.
    1. Biochemistry and Chemical Biology

    Regulation of mTORC1 by lysosomal calcium and calmodulin

    Ruo-Jing Li, Jing Xu ... Jun O Liu
    The multipronged chemical biology approach unraveled a novel mechanism by which mTOR is regulated by the second messenger calcium.
    1. Neuroscience

    Release-dependent feedback inhibition by a presynaptically localized ligand-gated anion channel

    Seika Takayanagi-Kiya, Keming Zhou, Yishi Jin
    An anion-selective ligand gated channel acts as a presynaptic auto-receptor to modulate vesicle release and neuronal excitation.
    1. Neuroscience

    Unique membrane properties and enhanced signal processing in human neocortical neurons

    Guy Eyal, Matthijs B Verhoog ... Idan Segev
    Models and experiments reveal that human L2/3 pyramidal neurons have distinctively low specific membrane capacitance which might have a significant impact on signal processing in human neocortex.
    1. Evolutionary Biology
    2. Neuroscience

    Evidence for evolutionary divergence of activity-dependent gene expression in developing neurons

    Jing Qiu, Jamie McQueen ... Giles E Hardingham
    The transcriptional response of human neurons to calcium ion signals shows evolutionary divergence from those responses elicited in mouse neurons, providing evidence in favour of using human systems to study neuronal responses to external stimuli.
    1. Biochemistry and Chemical Biology
    2. Immunology and Inflammation

    RING finger E3 ligase PPP1R11 regulates TLR2 signaling and innate immunity

    Alison C McKelvey, Travis B Lear ... Bill B Chen
    Novel post-translational modification of pattern recognition receptor TLR2 has consequences in bacterial infection and inflammatory signaling.
    1. Neuroscience

    Plasticity-dependent, full detonation at hippocampal mossy fiber–CA3 pyramidal neuron synapses

    Nicholas P Vyleta, Carolina Borges-Merjane, Peter Jonas
    Activity-dependent enhancement of transmitter release makes the hippocampal mossy fiber synapse a full detonator in rats.
    1. Cell Biology

    Curvature-induced expulsion of actomyosin bundles during cytokinetic ring contraction

    Junqi Huang, Ting Gang Chew ... Mohan K Balasubramanian
    Cytokinetic actomyosin ring disassembly occurs through a novel mechanism in which the increased ring curvature, generated through contraction, itself promotes the disassembly process.