Figure 3—figure supplement 2. | Social networks predict gut microbiome composition in wild baboons

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Social networks predict gut microbiome composition in wild baboons

Figure 3—figure supplement 2.

Affiliation details

Duke University, United States; National Museums of Kenya, Kenya; University of Montreal, Canada; University of Minnesota, United States; University of Notre Dame, United States; Princeton University, United States
Figure 3—figure supplement 2.
Download figureOpen in new tabFigure 3—figure supplement 2. Enrichment of low p-values in the data vs an empirical null: within group network analysis.

To confirm that our modeling approach (Moran's I statistic within Viola's group) did not bias us towards detecting false positives, we compared the signal in our true data set against an empirically derived null. The histogram distribution of p-values for the true data (gold) is plotted against the distribution of p-values from 10 permutations (blue). In each permutation, species abundance was scrambled across group members while keeping the modeling approach and social network structure constant. The inset shows a quantile–quantile plot of the same data, with clear enrichment of socially structured species in the actual data vs the empirical null. No socially structured species are detected at a 10% FDR in the permuted data sets, while 51 are discovered in the true data set.

DOI: http://dx.doi.org/10.7554/eLife.05224.013