63 results found
    1. Neuroscience

    The cerebellum linearly encodes whisker position during voluntary movement

    Susu Chen, George J Augustine, Paul Chadderton
    Cerebellar Purkinje cells represent movements via bidirectional linear changes in spike rate, and activity from single cells is sufficient to reconstruct kinematic changes during bouts of free whisking.
    1. Neuroscience

    Potentiation of cerebellar Purkinje cells facilitates whisker reflex adaptation through increased simple spike activity

    Vincenzo Romano, Licia De Propris ... Chris I De Zeeuw
    Physiological and behavioral analyses show that expression of cerebellar whisker learning can be mediated by increased simple spike activity, depending on LTP induction at parallel fiber to Purkinje cell synapses.
    1. Neuroscience

    Normal cognitive and social development require posterior cerebellar activity

    Aleksandra Badura, Jessica L Verpeut ... Samuel S-H Wang
    Social and cognitive functions require normal activity during development of the posterior cerebellum.
    1. Neuroscience

    VTA-projecting cerebellar neurons mediate stress-dependent depression-like behaviors

    Soo Ji Baek, Jin Sung Park ... Keiko Tanaka-Yamamoto
    Long-term chemogenetic manipulation of specific cerebellar pathway involving ventral tegmental area revealed a critical role of the pathway as a proactive mediator of the stress-dependent development of depression-like behaviors.
    1. Neuroscience

    Disynaptic cerebrocerebellar pathways originating from multiple functionally distinct cortical areas

    Julia U Henschke, Janelle MP Pakan
    Anatomical projections from sensory, motor, and association cortex to the cerebellum are precisely mapped, including cortical-precerebellar connections and terminal organization, providing insight into how the cerebellum may utilize cortical information.
    1. Neuroscience

    The cerebellum is involved in processing of predictions and prediction errors in a fear conditioning paradigm

    Thomas Michael Ernst, Anna Evelina Brol ... Dagmar Timmann
    Pronounced cerebellar activation during unexpected omission of a potentially harmful event suggests that the cerebellum has to be added to the neural network processing prediction errors underlying emotional associative learning.
    1. Medicine

    Correlated signatures of social behavior in cerebellum and anterior cingulate cortex

    Sung Won Hur, Karen Safaryan ... Peyman Golshani
    Development of a novel open-source device, 'E-Scope,' to simultaneously record electrophysiology and calcium imaging in freely behaving animals, discovering co-modulation of the cerebellum, and anterior cingulate cortex during social interaction.
    1. Neuroscience

    NINscope, a versatile miniscope for multi-region circuit investigations

    Andres de Groot, Bastijn JG van den Boom ... Tycho M Hoogland
    A light-weight, compact and open-source miniaturized fluorescence microscope integrates dual region brain imaging, optogenetic stimulation and behavioral parsing using an accelerometer.
    1. Stem Cells and Regenerative Medicine
    2. Chromosomes and Gene Expression

    Global reorganisation of cis-regulatory units upon lineage commitment of human embryonic stem cells

    Paula Freire-Pritchett, Stefan Schoenfelder ... Mikhail Spivakov
    Promoter interactome maps in human embryonic stem cells (ESCs) and ESC-derived early neuroectodermal progenitors link distal enhancers to putative target genes, reveal lineage-specific cis-regulatory architecture and shed light on the logic of gene regulation by multiple enhancers.
    1. Neuroscience

    Cerebellar involvement in an evidence-accumulation decision-making task

    Ben Deverett, Sue Ann Koay ... Samuel S-H Wang
    In a new evidence-accumulation decision-making task, activity of the lateral posterior cerebellum is necessary for accurate performance, and somatic and dendritic activity in Purkinje cells contains choice/evidence and error-related information.

Refine your results by:

Type
Research categories