The structure of a large enzyme complex involved in methanogenesis was determined at high resolution by electron cryo-microscopy.

A freely available software environment on Amazon's cloud computing network makes processing of cryo-EM data accessible and affordable.

The structure of a large hydrogenase complex involved in the production of methane by microbes has been determined with cryo-electron microscopy.

The first structure of the human epithelial sodium channel provides vital insight into the assembly, stoichiometry and molecular mechanism of the ion channel central to sodium homeostasis.

New hybrid structure determination methods leveraging the inherent biophysical properties of a macromolecule through molecular dynamics simulations provide accurate and cost-efficient ways of achieving atomic structures from high resolution cryo-electron density maps.

Keratins assemble into tubular filaments with a central density and exhibit structural heterogeneity, which is reflected in alterations of the helical arrangement.

SerialFIB is an adaptable open-source software designed for streamlining, advanced development and automation of cryo-focused ion beam-based cellular preparations for in situ cryo-electron tomography.

The resolution of electron cryo-microscopy can be improved by using optimal exposure values to filter video frames.

Structural insights into the architecture and functional properties of zebrafish TRPC4 are revealed by high-resolution cryo-EM.

The structure of human transcription factor IIH, a critical DNA repair and transcription initiation factor, has been determined by cryo-electron microscopy.