164 results found
    1. Cell Biology
    2. Physics of Living Systems

    Flagellar energetics from high-resolution imaging of beating patterns in tethered mouse sperm

    Ashwin Nandagiri, Avinash Satish Gaikwad ... Ranganathan Prabhakar
    Calculations of flagellar energetics from beating patterns in sperm reveal that internal dissipation by dynein motors and other passive structures within the flagellum significantly exceeds external hydrodynamic dissipation.
    1. Physics of Living Systems

    The biomechanical role of extra-axonemal structures in shaping the flagellar beat of Euglena gracilis

    Giancarlo Cicconofri, Giovanni Noselli, Antonio DeSimone
    The 'spinning lasso' geometry of Euglena's beating flagellum is revealed, and a model based on the antagonistic forces exchanged by axoneme and paraflagellar rod is proposed to explain its emergence.
    1. Physics of Living Systems
    2. Cell Biology

    Dynamic curvature regulation accounts for the symmetric and asymmetric beats of Chlamydomonas flagella

    Pablo Sartori, Veikko F Geyer ... Jonathon Howard
    The self-organised beat of cilia and flagella is dynamically regulated by curvature.
    1. Cell Biology

    Intraflagellar transport drives flagellar surface motility

    Sheng Min Shih, Benjamin D Engel ... Ahmet Yildiz
    The transport of proteins along flagellar microtubules generates the force that enables flagella to propel cells across surfaces.
    1. Cell Biology

    Testing the ion-current model for flagellar length sensing and IFT regulation

    Hiroaki Ishikawa, Jeremy Moore ... Wallace F Marshall
    A model for flagellar length control based on calcium influx is rejected based on quantitative measurements in Chlamydomonas cells.
    1. Microbiology and Infectious Disease
    2. Physics of Living Systems

    Coordination of two opposite flagella allows high-speed swimming and active turning of individual zoospores

    Quang D Tran, Eric Galiana ... Xavier Noblin
    Coordinated actions of two opposite flagella control speed and change direction of plant pathogen Phytophthora zoospores, in which the anterior flagellum is the main motor to generate thrust and spontaneously switch from reciprocal beating to breaststrokes to reorient its body.
    1. Developmental Biology
    2. Physics of Living Systems

    Rolling controls sperm navigation in response to the dynamic rheological properties of the environment

    Meisam Zaferani, Farhad Javi ... Alireza Abbaspourrad
    Rheological properties of the environment regulate sperm swimming and navigational behavior through suppression or reactivation of sperm rolling around its longitudinal axis.
    1. Physics of Living Systems
    2. Cell Biology

    Flagellar synchronization through direct hydrodynamic interactions

    Douglas R Brumley, Kirsty Y Wan ... Raymond E Goldstein
    A combination of experiment and theory shows that pairs of eukaryotic flagella can achieve robust synchronization solely through the action of the fluid that surrounds them.
    1. Physics of Living Systems

    Strong confinement of active microalgae leads to inversion of vortex flow and enhanced mixing

    Debasmita Mondal, Ameya G Prabhune ... Prerna Sharma
    Coupling between cell motility and strong confinement alters the force generators that cause flow fields to change their handedness and lead to enhanced mixing.
    1. Genetics and Genomics

    Novel axonemal protein ZMYND12 interacts with TTC29 and DNAH1, and is required for male fertility and flagellum function

    Denis Dacheux, Guillaume Martinez ... Charles Coutton
    Bi-allelic mutations in ZMYND12, encoding a novel axonemal protein interacting with TTC29 and DNAH1, cause male infertility and flagellum defects in human and Trypanosoma.

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