Sudeshna Das Chakraborty, Hetan Chang ... Silke Sachse
Two-photon functional imaging linked to olfactory preference in Drosophila provides the first understanding of how odors are integrated, transformed, and represented in the lateral horn by an ensemble of higher-order glutamatergic lateral horn neurons.
Michael-John Dolan, Shahar Frechter ... Gregory SXE Jefferis
The generation and systematic characterisation of driver lines labelling a large number of neurons in the Drosophila innate olfactory processing centre bridges electron microscopy neuronal reconstructions, circuits and behaviour.
Philipp Schlegel, Alexander Shakeel Bates ... Gregory S X E Jefferis
Synaptic resolution analysis of a full olfactory connectome reveals lateralised circuits, convergence of innate and learned pathways, and shows that homologous neurons are highly stereotyped within and across brains.
A combination of genetic, anatomical and physiological techniques has revealed that the lateral horn, a region of the brain involved in olfaction in flies, has many more types of neurons than expected.
Shahar Frechter, Alexander Shakeel Bates ... Gregory Jefferis
The Drosophila lateral horn, a higher olfactory brain area, contains >165 genetically defined cell types with stereotyped odour responses across animals and improved odor categorisation compared with their inputs.
Ourania Semelidou, Summer F Acevedo, Efthimios MC Skoulakis
Habituation to brief olfactory stimulation is biphasic and mediated by distinct neuronal circuits where an initial latency phase is rapidly followed by stimulus devaluation signifying behavioral habituation in Drosophila.
Robert Philip Ganley, Marilia Magalhaes de Sousa ... Hanns Ulrich Zeilhofer
Two populations of serotonergic neurons are present in the medial and lateral hindbrain, which are shown to project to distinct spinal cord regions and have opposing effects on nociception in mice.
Advanced genetics and imaging reveal wiring logic underlying the olfactory map organization in the developing fruit fly brain, and strategies employed by projection neurons to target dendrites to specific locations in a timely manner.
