1,783 results found
    1. Evolutionary Biology

    Social and environmental predictors of gut microbiome age in wild baboons

    Mauna R Dasari, Kimberly E Roche ... Elizabeth A Archie
    The mammalian gut microbiome can be used as a noninvasive and holistic predictor of biological age.
    1. Ecology
    2. Microbiology and Infectious Disease

    Universal gut microbial relationships in the gut microbiome of wild baboons

    Kimberly E Roche, Johannes R Bjork ... Elizabeth A Archie
    In baboon gut microbiota, most pairwise correlations in bacterial abundances are weak and negative, and bacterial correlation patterns are largely shared across hosts, rather than personalized to each hosts.
    1. Ecology
    2. Epidemiology and Global Health

    Microbiome-pathogen interactions drive epidemiological dynamics of antibiotic resistance: A modeling study applied to nosocomial pathogen control

    David RM Smith, Laura Temime, Lulla Opatowski
    A novel mathematical modeling framework for antibiotic-resistant bacteria combining within-host microbiome-pathogen interactions with population-level pathogen epidemiology, demonstrating how antibiotic consumption and ecological competition come together to drive the spread of resistance.
    1. Microbiology and Infectious Disease

    Host genetic selection for cold tolerance shapes microbiome composition and modulates its response to temperature

    Fotini Kokou, Goor Sasson ... Itzhak Mizrahi
    Microbiome and transcriptomic profiling of genetically selected tropical fish with high and low tolerance to cold exposure revealed host control over microbiome composition and response to temperature changes.
    1. Ecology
    2. Evolutionary Biology

    Effects of domestication on the gut microbiota parallel those of human industrialization

    Aspen T Reese, Katia S Chadaideh ... Rachel N Carmody
    Gut microbial signatures of domestication parallel those of industrialization, implicating shared ecological drivers.
    1. Computational and Systems Biology
    2. Ecology

    Microbes with higher metabolic independence are enriched in human gut microbiomes under stress

    Iva Veseli, Yiqun T Chen ... A Murat Eren
    Higher biosynthetic capacity of gut microbes in individuals diagnosed with noncommunicable diseases or taking antibiotics suggests that diversity loss and 'dysbiosis' result from microbiome restructuring in response to ecosystem disruption.
    1. Cell Biology

    Protein absorption in the zebrafish gut is regulated by interactions between lysosome rich enterocytes and the microbiome

    Laura Childers, Jieun Park ... Michel Bagnat
    The gut microbiome regulates protein absorption activity in lysosome-rich enterocytes (LREs) and causes broad gene expression changes, while LRE activity also affects the microbiome.
    1. Microbiology and Infectious Disease

    The East Asian gut microbiome is distinct from colocalized White subjects and connected to metabolic health

    Qi Yan Ang, Diana L Alba ... Peter J Turnbaugh
    The gut microbiota of East Asians is distinct, dissociated from body mass, and self-sustains compared to White subjects from the same region, and therein may underpin a key health disparity.
    1. Computational and Systems Biology
    2. Microbiology and Infectious Disease

    Microbial genetic and transcriptional contributions to oxalate degradation by the gut microbiota in health and disease

    Menghan Liu, Joseph C Devlin ... Lama Nazzal
    A novel multi-omics framework revealed the taxonomic contribution to microbiota oxalate, demontrated O. formigenes as the dominating taxon transcriptionally, and identified specific IBD cohort at risk for oxalte toxicity.
    1. Computational and Systems Biology
    2. Microbiology and Infectious Disease

    Modeling transfer of vaginal microbiota from mother to infant in early life

    Martin Steen Mortensen, Morten Arendt Rasmussen ... Søren Johannes Sørensen
    Modeling weighted transfer ratios enable statistical analysis of maternal–infant transfer at a more general level and can indicate whether any transfer is persistent, transient, or originates from alternate sources.

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