Focal optogenetic stimulation strengthens functional connectivity between primary somatosensory and motor cortices in macaques, in a manner consistent with a Hebbian model of stimulus-driven plasticity.

Optogenetic activation of Rho GTPases provides spatiotemporal control over endothelial cell shape and enables control over endothelial barrier function by manipulating the cell-cell overlap with blue light.

The optogenetic manipulation of hippocampal neuronal circuit activity revealed plastic changes of pyramidal-interneuron connections in behaving animals, which were primarily governed by the firing rate change of postsynaptic interneurons.

Trafficking of optogenetic tools to primary cilia using nanobodies allows to study cAMP signaling with spatial and temporal resolution independent of the cell body.

A simple, computationally efficient method provides spatiotemporally precise optogenetic perturbations in freely walking Drosophila, revealing the asymmetries and region-specificity of behavioral programs evoked by activating mechanosensory and chemosensory neurons.

A combination of multicellular recording and optogenetic photostimulation was used to deeply characterize the spatial profiles and effective strengths of intralaminar and translaminar synaptic connections from genetically defined neuronal populations in the visual cortex of adult mouse.

The visual thalamus is a promising target for neural prosthetic intervention aimed at the restoration of visual function.

Interactions between near but distinct (<1 mm) structures such as cortical layers in the rodent brain can be studied by a new micro-optical tool that is low-cost and capable of multilayer optical recordings, optogenetic stimulations, or both.

Phasic activation of dorsal raphe serotonin neurons transiently inhibits locomotion without influencing anxiety or producing reinforcement, but when repeated over many days a long-term facilitation of locomotion is produced.

A near-infrared light-stimulable optogenetic platform enables remote and wireless manipulation of calcium signaling and immune responses both in vitro and in vivo to achieve tailored function.