A transcription factor called Lhx1 coordinates the activity of the brain's master circadian clock, the suprachiasmatic nucleus, by controlling communication between its constituent cells.

Conditional deletion of Bmal1 in the forebrain/SCN reveals an essential role of a functional master clock in maintaining synchronized and high amplitude rhythms of peripheral clocks.

Daily fluctuations versus transient perturbations in environmental light influence behavior and physiology through distinct circuits.

Circadian control of neuronal excitability in the master circadian clock of a diurnal mammal as revealed by whole-cell recording and mathematical modeling.

A seasonal switch to excitatory GABAA signaling dictates how daily clock neurons interact to encode environmental change.

Cyclin-dependent kinase 5 regulates the circadian clock involving phosphorylation of the PER2 protein.

RNA sequencing reveals the finer details of circadian variation in the mammalian master pacemaker over 24 hours, which suggests that transcriptional timing influences clock resetting mechanisms.

A single subpopulation of photoreceptors constitutes a shared node in the neural networks that regulate light-dependent maturation of the circadian clock and light-independent refinement of retinal ganglion cell projections to the brain.

Sleep-wake patterns, together with a suprachiasmatic nuclei-independent circadian factor, are necessary and sufficient to maintain high-amplitude nychthemeral rhythms in PERIOD-2.

The zinc finger protein ZBTB20 is a morning and evening activity gating factor in mice.