Genome sequence data from 58 Mexican swine influenza A viruses resolves the spatial origin of the virus that originated the influenza pandemic of 2009.

Swine populations worldwide are sporadically infected by influenza viruses from humans and birds leading to geographically heterogeneous swine influenza virus populations that pose epizootic and pandemic threats.

Live imaging and genetic analyses revealed that notochord vacuoles play a critical role in spine morphogenesis by absorbing vertebral bone growth, thus implicating notochord mechanics in congenital scoliosis.

The abundance and complex genetic diversity of swIAV were documented and the zoonotic potential evaluated.

The flexible network architecture of the brain is sensitive to the modulation of neural gain, which may be mediated by ascending arousal nuclei, such as the noradrenergic locus coeruleus.

Lesions to the anterior-medio-dorsal thalamus cause widespread behavioral impairments across multiple cognitive domains, suggesting that thalamic hubs are critical for interconnecting diverse cognitive processes.

SINE RNAs are implicated in amyloid beta molecular pathology in hippocampus.

Mutating a highly conserved intramembrane salt bridge unmasks structural and functional coupling between channel gating and ion permeation in the muscle nicotinic receptor.

The determination that a decision-maker integrated evidence to form perceptual decisions is shown to be much more difficult than previously appreciated.

Infection experiments in ferrets reveal swine influenza viruses need their hemagglutinin antigen to become stabilized for transmissibility, adding a new property to consider when triaging field isolates for pandemic potential.