Loss of T cell control during persistent polyomavirus infection, in the setting of a limited antiviral antibody response, facilitates emergence of antibody-escape viruses carrying the potential for neurovirulence.

LMO2 plays an important role in the maintenance of T lymphocyte competence and survival of pre-thymic progenitors by regulating the expression of Bcl11a and Tcf7 genes.

Myc-dependent induction of amino acid transporter expression in response to T cell receptor activation is essential to enable T cell proteome remodelling upon immune activation.

SLAMF6 is an inhibitory checkpoint of T cells, the lack of which leads to better tumor control, suggesting a new immunotherapy target.

Identification and characterization of the responses of T lymphocytes that are specific for 'self' tissue antigens, revealing the functional limits of immune tolerance.

The transcriptional adapter protein NCOR1 that links chromatin-modifying enzymes with gene-specific transcription factors controls naive and effector regulatory T cell states.

IL-6 signaling in T cells controls how sensitive they are to suppression by T regulatory cells, and the way mature to become memory T cells.

T cell receptor signaling is regulated by newly polymerized F-actin foci at the immunological synapse.

Structurally dissimilar N-glycans can be functionally equivalent, and are produced via a self-correcting feature of the Golgi.

Development of mouse thymocytes through the pre-TCR checkpoint requires WNK1 kinase signalling via the OXSR1 and STK39 kinases and the SLC12A2 ion co-transporter leading to MYC-dependent cell proliferation.