We provide a tutorial to use GAMLSS, applied using cohort data to study how risk factors may influence both the mean and variability of body mass index and mental health.
Raphaël Etournay, Matthias Merkel ... Frank Jülicher
A computational framework called TissueMiner, complete with tutorials, will allow a wide range of users to perform quantitative multiscale analysis of tissue morphogenesis.
Samuel A Neymotin, Dylan S Daniels ... Stephanie R Jones
Human Neocortical Neurosolver is a new user-friendly software tool for researchers to develop and test hypotheses on cellular/circuit origins of human MEG/EEG signals using a biophysical model.
The BigBrainWarp toolbox facilitates integration of 3D human brain histology with neuroimaging, helping neuroscientists to utilise cytoarchitectural information in conjunction with in vivo imaging.
FlyBrainLab is an open-source computing platform that integrates 3D exploration and visualization of diverse Drosophila connectomic/synaptomic datasets with interactive exploration of the functional logic of modeled executable brain circuits.
Barbora Rehak Buckova, Charlotte Fraza ... Jaroslav Hlinka
Normative modelling adapted for longitudinal neuroimaging enables precise evaluation of individual brain changes over time, revealing subtle disease dynamics and temporal patterns missed by traditional analytical approaches.
SerialFIB is an adaptable open-source software designed for streamlining, advanced development and automation of cryo-focused ion beam-based cellular preparations for in situ cryo-electron tomography.
Marcel Beining, Lucas Alberto Mongiat ... Peter Jedlicka
T2N, a novel interface between Matlab, TREES toolbox and NEURON, was used to generate compartmental models that reproduce the electrophysiology of dentate granule cells over a multitude of species, experimental conditions and developmental stages.
Dipak N Patil, Erumbi S Rangarajan ... Kirill A Martemyanov
Atomic details on structural organization and conformational dynamics of the key regulator of neuronal signaling shed light on its allosteric regulation and role in regulating cellular pathways.
Inspired by the sparse, sequential neural activity patterns observed in striatum, a new circuit model implements variable-speed activity, the encoding of multiple sequences, and a tutor/student relationship between cortex and striatum.