Amy Richardson, Victoria Ciampani ... Ian D Forsythe
The Kv3.3 potassium channel subunit is necessary and sufficient to permit presynaptic location and accelerated repolarisation of the presynaptic action potential, thereby conserving resources and enhancing accuracy of timing information on transmission at the calyx of Held excitatory synapse.
Electrochemical recordings of cortico-striatal glutamatergic signaling, and chemogenetic inhibition of such signaling, revealed an essential role of cortico-striatal input for cued action selection, but not for cued stopping.
The secondary motor cortex causally contributes to flexible action selection during stimulus categorization with the representations of upcoming choice and sensory history regulated by the demand to remap stimulus–action association.
A new method for analyzing continuous psychophysics experiments estimates not only perceptual uncertainty from tracking tasks but also action variability, intrinsic costs, and subjective internal models.
Niklas Byczkowicz, Abdelmoneim Eshra ... Stefan Hallermann
The cAMP-HCN pathway can control action potential conduction velocity providing neuromodulators with the ability to tune energy consumption and temporal delays across axons in the brain.
Brad K Hulse, Hannah Haberkern ... Vivek Jayaraman
An analysis of the first complete synaptic resolution connectome of Drosophila's navigation circuit uncovers neural network motifs supporting broadly relevant sensorimotor computations.
Jacqueline Katharina Meier, Bernhard P Staresina, Lars Schwabe
Decoding of neural outcome and response representations allows dissecting goal-directed and habitual contributions to behaviour and reveals how acute stress biases the instrumental control of behaviour.
Imaging experiments reveal that some brain regions do not distinguish between actions performed using tools and those performed using the hands, while others represent these two types of action separately.