Mammalian neural stem cells specifically regulate a subset of astral microtubules to govern the subtle changes in spindle orientation that underlie symmetric vs asymmetric cell division during embryonic cortical neurogenesis.

Live imaging of multiple cytoplasmic networks in frog egg extracts calls for new models for how egg cytoplasm is physically organized during cleavage divisions.

Optogenetic reconstitution reveals core functional modules and architecture of the cortical force-generating machinery in human cells.

A protein kinase complex that is important for cell division is lost in testicular seminoma, which is a common cancer in men.

Stoichiometric interactions between microtubules and cortical force-generators set spindle size, position and dynamics, and its scaling with cell size in nematode species.

MT plus-end-mediated recruitment of a cortical pool of ECT2 trigger RhoA activation upon contact, which results in localized contractility during cytokinesis.

A mechanism for yeast centrosomes to differentiate the microtubule cytoskeleton.

STED microscopy of human mitotic spindles reveals how augmin-nucleated microtubules protect the cell from erroneous kinetochore-microtubule attachments and ensure a highly organized architecture of the spindle required for mitotic fidelity.

Super-resolution microscopy, biochemical and functional analyses reveal how α-taxilin and γ-taxilin are assembled at the subdistal appendages and their roles in microtubule organization.

Cell geometry and polarity domains act in concert to determine spindle positioning, with cell geometry modulating the effect of cortical polarity domains by influencing the position of the spindle relative to those polarity domains.