25 results found
    1. Neuroscience

    NeuroQuery, comprehensive meta-analysis of human brain mapping

    Jérôme Dockès, Russell A Poldrack ... Gaël Varoquaux
    Full-text analysis of the human brain-imaging literature can predict the spatial distribution of observations in the brain given the description of a subject of study.
    1. Neuroscience

    Topographic gradients of intrinsic dynamics across neocortex

    Golia Shafiei, Ross D Markello ... Bratislav Misic
    Intrinsic dynamics are shaped by the intersection of molecular, microstructural, connectomic, and activation gradients.
    1. Immunology and Inflammation

    The meningeal transcriptional response to traumatic brain injury and aging

    Ashley C Bolte, Daniel A Shapiro ... John R Lukens
    Transcriptional analyses provide an atlas of how traumatic brain injury and aging shape meningeal cell composition and gene expression.
    1. Cell Biology
    2. Neuroscience

    APOE expression and secretion are modulated by mitochondrial dysfunction

    Meghan E Wynne, Oluwaseun Ogunbona ... Victor Faundez
    Current models of Alzheimer's disease that put mitochondria as an endpoint of disease should be reconsidered because genetic defects affecting mitochondria by themselves can also regulate Alzheimer’s disease risk factor apolipoprotein E (APOE) expression and secretion.
    1. Neuroscience

    Functional gradients in the human lateral prefrontal cortex revealed by a comprehensive coordinate-based meta-analysis

    Majd Abdallah, Gaston E Zanitti ... Demian Wassermann
    A comprehensive meta-analysis of the neuroimaging literature reveals that the lateral prefrontal cortex of humans is mainly organized along its rostrocaudal axis according to a unimodal-to-transmodal pattern of network connectivity and a concrete-to-abstract axis of functional associations.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Virus infection of the CNS disrupts the immune-neural-synaptic axis via induction of pleiotropic gene regulation of host responses

    Olga A Maximova, Daniel E Sturdevant ... Alexander G Pletnev
    Virus infection of the central nervous system disrupts the homeostasis of the immune-neural-synaptic axis via induction of pleiotropic genes with an unintended off-target negative impact on the neurotransmission.
    1. Neuroscience

    PAK3 downregulation induces cognitive impairment following cranial irradiation

    Haksoo Lee, Hyunkoo Kang ... BuHyun Youn
    p21-activated kinase 3 (PAK3) is a factor related to radiation-induced cognitive decline, and it has been found that regulating it leads to the recovery of cognitive decline induced by radiation.
    1. Neuroscience

    The OpenNeuro resource for sharing of neuroscience data

    Christopher J Markiewicz, Krzysztof J Gorgolewski ... Russell Poldrack
    OpenNeuro is a data sharing archive that provides a platform for the free and open sharing of a broad range of neuroscience data types.
    1. Genetics and Genomics
    2. Neuroscience

    MicroRNA-eQTLs in the developing human neocortex link miR-4707-3p expression to brain size

    Michael J Lafferty, Nil Aygün ... Jason L Stein
    Inter-individual differences in miRNA expression during fetal cortical development informs genetic mechanisms for complex brain phenotypes.
    1. Immunology and Inflammation
    2. Neuroscience

    Time-dependent cytokine and chemokine changes in mouse cerebral cortex following a mild traumatic brain injury

    David Tweedie, Hanuma Kumar Karnati ... Nigel H Greig
    Protein changes in cerebral cortex following a mild traumatic brain injury (mTBI) identified herein will help in the development of monitoring and response biomarkers that may translate to clinical mTBI.

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