199 results found
    1. Microbiology and Infectious Disease

    FtsK is critical for the assembly of the unique divisome complex of the FtsZ-less Chlamydia trachomatis

    McKenna Harpring, Junghoon Lee ... John V Cox
    The novel divisome complex of Chlamydia trachomatis contains elements of the divisome and elongasome from other bacteria, and it requires the chromosomal translocase, FtsK, for its assembly.
    1. Neuroscience

    A visual sense of number emerges from divisive normalization in a simple center-surround convolutional network

    Joonkoo Park, David E Huber
    A set of canonical computational principles implemented in a simple feedforward neural network naturally gives rise to the network's sensitivity to numerosity and its illusory effects, providing an explanation for the ubiquity of the number sense in the animal kingdom.
    1. Neuroscience

    Divisive suppression explains high-precision firing and contrast adaptation in retinal ganglion cells

    Yuwei Cui, Yanbin V Wang ... Daniel A Butts
    The convergence of two visual pathways at the level of retinal bipolar cells accounts for key features of ganglion cell responses.
    1. Neuroscience
    2. Developmental Biology

    Intraparietal stimulation disrupts negative distractor effects in human multi-alternative decision-making

    Carmen Kohl, Michelle XM Wong ... Bolton KH Chau
    Divisive normalisation effects on decision making caused by distractor options can be reduced by stimulating the parietal cortex using transcranial magnetic stimulation.
    1. Microbiology and Infectious Disease

    A unique cell division protein critical for the assembly of the bacterial divisome

    Xiao Chu, Lidong Wang ... Zhaoqing Luo
    Identifying gain-of-function division variants that suppress the elongated cell division defect phenotype caused by Aeg1 depletion.
    1. Neuroscience

    Consistent patterns of distractor effects during decision making

    Bolton KH Chau, Chun-Kit Law ... Matthew FS Rushworth
    The value of any choice is not static but dynamically changes as a function of the context of the alternatives even if they are seemingly irrelevant.
    1. Cell Biology
    2. Chromosomes and Gene Expression

    Aneuploidy as a cause of impaired chromatin silencing and mating-type specification in budding yeast

    Wahid A Mulla, Chris W Seidel ... Rong Li
    Genetic analyses reveal that purely quantitative changes in the relative copy number of chromosomes can be sufficient to disrupt the epigenetic mechanisms that define the cells' differentiated state.
    1. Microbiology and infectious disease

    Asymmetric division triggers cell-specific gene expression through coupled capture and stabilization of a phosphatase

    Niels Bradshaw, Richard Losick
    Asymmetric cell division is linked to cell-specific transcription by handoff of a key developmental regulator from the cytokinetic machinery to the adjacent cell pole where it oligomerizes to become stabilized and activated.
    1. Microbiology and Infectious Disease

    Staphylococcus aureus FtsZ and PBP4 bind to the conformationally dynamic N-terminal domain of GpsB

    Michael D Sacco, Lauren R Hammond ... Yu Chen
    The N-terminal domain of Staphylococcus aureus GpsB, a scaffolding protein, forms an atypical asymmetric dimer and binds to the C-termini of FtsZ and PBP4, influencing the localization and regulation of both the Z-ring and cell wall synthesis.
    1. Neuroscience

    Working memory capacity of crows and monkeys arises from similar neuronal computations

    Lukas Alexander Hahn, Dmitry Balakhonov ... Jonas Rose
    Despite differences in cellular architecture the brains of monkeys and crows produce comparable limits of working memory with comparable mechanisms.

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