4,868 results found
    1. Neuroscience

    Effects of clozapine-N-oxide and compound 21 on sleep in laboratory mice

    Janine Traut, Jose Prius Mengual ... Lukas B Krone
    The two most commonly used chemogenetic actuators, clozapine-N-oxide and compound 21, similarly modulate sleep in wild-type laboratory mice indicating that even designer drugs which do not convert to clozapine can elicit behavioural effects and require adequate controls.
    1. Neuroscience

    High-throughput microcircuit analysis of individual human brains through next-generation multineuron patch-clamp

    Yangfan Peng, Franz Xaver Mittermaier ... Jörg Rolf Paul Geiger
    Combining a multineuron patch-clamp system with an automated pipette pressure and cleaning device enables efficient screening of synaptic connectivity in human brain slices and allows inter-individual comparison.
    1. Ecology
    2. Neuroscience

    Patterns of call communication between group-housed zebra finches change during the breeding cycle

    Lisa F Gill, Wolfgang Goymann ... Manfred Gahr
    Call-based vocal communication of individually recorded zebra finches changes in social groups across reproductive stages and is related with successful egg laying.
    1. Neuroscience

    Cortex-wide BOLD fMRI activity reflects locally-recorded slow oscillation-associated calcium waves

    Miriam Schwalm, Florian Schmid ... Albrecht Stroh
    Locally recorded calcium events related to slow wave activity show a global cortical fMRI BOLD correlate, establishing a direct relation between a basic neurophysiological signal and the macroscopic perspective of pre-clinical fMRI.
    1. Computational and Systems Biology
    2. Neuroscience

    A quantitative model of conserved macroscopic dynamics predicts future motor commands

    Connor Brennan, Alexander Proekt
    Calcium imaging is used to construct a model of Caenorhabditis elegans nervous system dynamics capable of predicting future behavioral switches on a trial by trial basis and across individual animals.
    1. Neuroscience

    Tracking individual action potentials throughout mammalian axonal arbors

    Milos Radivojevic, Felix Franke ... Douglas J Bakkum
    A method was developed to non-invasively and simultaneously track individual action-potentials propagating across multiple branches of identified neurons in neocortical cultures.
    1. Genetics and Genomics
    2. Neuroscience

    Tyramine and its Amtyr1 receptor modulate attention in honey bees (Apis mellifera)

    Joseph S Latshaw, Reece E Mazade ... Brian Smith
    Genetic variation in a biogenic amines receptor underlies a means of gain control for nonassociative learning and hence an important form of attention that is the basis for tradeoffs in foraging in a social collective.
    1. Neuroscience

    A synergy-based hand control is encoded in human motor cortical areas

    Andrea Leo, Giacomo Handjaras ... Emiliano Ricciardi
    The human brain encodes coordinated patterns of joint movements – synergies – to increase the efficiency with which it can control complex hand movements.
    1. Neuroscience

    Descending neuron population dynamics during odor-evoked and spontaneous limb-dependent behaviors

    Florian Aymanns, Chin-Lin Chen, Pavan Ramdya
    In the fly, Drosophila melanogaster, the population activity of descending neurons (DNs) projecting from the brain to the motor system is predominantly correlated with locomotion with only a few DNs encoding grooming or olfactory signals in the absence of behavior.
    1. Neuroscience

    Myomatrix arrays for high-definition muscle recording

    Bryce Chung, Muneeb Zia ... Samuel J Sober
    A novel technology for recording muscle activity provides unprecedented access to the electrical signals that control the body across muscles, species, and behaviors.

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