Tricellular vertices possess sliding behaviors that harness radial forces and drive cell shape changes and intercalation in an epithelial tissue.

Analysing Myosin II unipolar planar polarisation with high spatial and temporal resolution during Drosophila axis extension reveals how tissue boundaries drive polarized cell intercalation while limiting cell mixing.

Active and passive contributions to cell shape change and rearrangements can be distinguished from observed cell geometry, revealing the self-organization mechanisms underlying internally-driven epithelial convergent extension.

Geometric criteria can be used to assess whether cell intercalation is active or passive during the convergent extension of tissue.

Planar cell polarity proteins display dynamic spatial and temporal patterns of enrichment that tightly correlate with myosin-dependent cell behaviors during neural tube closure.

Directed mechanical stresses can trigger active T1 events that lead to tissue elongation perpendicular to the main direction of tissue stress.

Quantitative analysis in quasi-3D reveals apically driven cell behaviours that are closely coordinated across the tissue to allow ordered tube invagination through a focal point.

During the morphogenesis of the tubes of the salivary glands in the fly embryo, a correct regionalization of the flat epithelial primordium by upstream transcription factors is key to drive coordinated changes in cell behavior.

Through the interaction between PCP signaling and N-cadherin, oriented cell division and cell rearrangement are coordinated to establish the appropriate tissue architecture critical for limb skeletal morphogenesis.

Direct live-cell imaging of human cells, combined with RNA-seq, qPCR and in vitro reconstitution essays, reveal that mitotic progression, arrest, exit or death is independent of de novo transcription.