State-of-the-art knowledge of microscopic colitis, a disease often more prevalent than ulcerative colitis and Crohn’s disease among elderly people, is provided from a global perspective with the overall aim to create better awareness and improve rational management.

Treatment with a JAK inhibitor normalizes multiple biomarkers of autoinflammation and provides therapeutic benefit for diverse immune skin conditions in individuals with Down syndrome.

Reprogramming of transcription factors by PRR-independent (cAMP) and PRR-dependent (curdlan) signaling induces new dendritic cell subset.

In contrast with earlier conclusions, negative selection has a major role in cancer evolution.