2,654 results found
    1. Stem Cells and Regenerative Medicine

    The neural crest is a source of mesenchymal stem cells with specialized hematopoietic stem cell niche function

    Joan Isern et al.
    Developing long bones contain distinct mesenchymal stem-cell populations derived from mesoderm and neural crest, which have specialized functions in skeleton formation and the establishment of the hematopoietic stem-cell niche, respectively.
    1. Stem Cells and Regenerative Medicine

    Embryonic attenuated Wnt/β-catenin signaling defines niche location and long-term stem cell fate in hair follicle

    Zijian Xu et al.
    Long-term hair follicle stem cells arise by embryonic progenitor cells occupying a niche location that is defined by attenuated Wnt/β-catenin signal.
    1. Stem Cells and Regenerative Medicine

    Wnt signaling-mediated redox regulation maintains the germ line stem cell differentiation niche

    Su Wang et al.
    Wnt signaling regulates cellular redox in the germline stem cell differentiation niche via a novel regulatory mechanism, thereby controlling germ line stem cell progeny differentiation.
    1. Stem Cells and Regenerative Medicine

    Hematopoietic stem and progenitor cells regulate the regeneration of their niche by secreting Angiopoietin-1

    Bo O Zhou et al.
    Normal hematopoietic stem and progenitor cells slow the regeneration of their niche after injury to minimize leakage from the niche vasculature.
    1. Cell Biology
    2. Developmental Biology

    Hepatocyte Growth Factor-mediated satellite cells niche perturbation promotes development of distinct sarcoma subtypes

    Deborah Morena et al.
    The functional relevance of stem cell niche perturbation in sarcomagenesis is defined and the mouse model presented provides a rationale for the use of combination therapy for the treatment of genetically heterogeneous sarcomas.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Updates to the zoonotic niche map of Ebola virus disease in Africa

    David M Pigott et al.
    Building on previous work (Pigott et al. 2014), estimates of areas of potential transmission of Ebola virus are revised and updated to provide a contemporary map for use by researchers and policymakers.
    1. Neuroscience

    Injury-induced perivascular niche supports alternative differentiation of adult rodent CNS progenitor cells

    Justyna Ulanska-Poutanen et al.
    Distinctive microenvironments within demyelinated white matter determine fate decisions of adult oligodendrocyte progenitor cells.
    1. Stem Cells and Regenerative Medicine

    Stem cells repurpose proliferation to contain a breach in their niche barrier

    Kenneth Lay et al.
    Adult stem cells sense nearby tissue damage and recruit immune cells to help them direct efforts towards containing a breach in the epithelial barrier.
    1. Ecology

    Regularities in species’ niches reveal the world’s climate regions

    Joaquín Calatayud et al.
    Similarities in climatic niches of terrestrial vertebrates indicate the Earth's climate regions, which differ among groups and from previous plant-based climate classifications.
    1. Developmental Biology

    The vascular niche controls Drosophila hematopoiesis via fibroblast growth factor signaling

    Manon Destalminil-Letourneau et al.
    Two niches contribute to the control of Drosophila blood cell homeostasis through their differential regulation of hematopoietic progenitors.

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