A high-resolution, high-speed tissue imaging analysis reveals how neural and muscular tissues coordinate during planarian growth and regeneration.

Predicted gene regulatory networks active in planarians adult stem cells provide testable hypotheses about the control of pluripotency and differentiation in animals.

A chemical method has been developed for studying single organ regeneration and fate specification of stem cells in an adult organism.

Single-cell RNA sequencing identifies an adult regional gene expression map in planarian muscle that includes two FGFRL-Wnt circuits controlling head and trunk tissue pattern.

Loss of a single organ, the planarian pharynx, triggers immediate proliferation and expansion of stem cells required to replace it.

Application of laser-capture microdissection to planarian intestinal tissue provides a new tool for analysis of tissue-specific gene expression in flatworms, and a new resource to advance investigations of gastrointestinal regeneration.

A combination of experimental and theoretical analysis identifies body size-dependent energy storage as the physiological cause of 3/4-power law scaling of the metabolic rate in planarians.

Hedgehog signaling plays a role in regulating glia gene expression in planarians, pointing to a candidate ancestral and broadly used role for the Hedgehog pathway.

NR4A is a broadly conserved transcription factor that is required for concordance of patterning information and anatomy at both ends of the planarian anterior-posterior axis.

The planarian mex3-1 gene is required for non-stem cell fates and suppresses a stem cell fate in differentiating cells.