Tgfbr1 signaling governs all processes associated with the trunk to tail transition, including the repositioning of neuro-mesodermal progenitors, as well as the remodeling of the lateral plate mesoderm and embryonic endoderm.

NR4A is a broadly conserved transcription factor that is required for concordance of patterning information and anatomy at both ends of the planarian anterior-posterior axis.

Hox genes are activated sequentially and, at the same time, undergo a transition from an inactive to an active chromatin compartment, most likely to prevent posterior genes being activated too early.

After complete spinal transection in adult rats, careful combinations of pharmacological and physical therapies create a novel cortical sensorimotor circuit that may bypass the lesion through biomechanical coupling, allowing animals to recover unassisted hindlimb locomotion.

A thorough insight into the previously unrecognised role of a critical developmental regulator known as TBXT in influencing the specification of human trunk neural crest cells, the presumed precursors of the childhood tumour neuroblastoma.

Shared complexities of backbone segmentation between cartilaginous fishes and tetrapods originate much earlier in vertebrate evolution than previously thought.

During vertebrate axial extension, the tail bud originates from the activation of a developmental module in a subset of axial progenitors, concurrent but different to gastrulation.

A digital flesh model of the sail-backed dinosaur Spinosaurus was tested and performed very poorly in water, favoring the view of this dinosaur as a two-legged, wading ambush predator of large fish in shallow waterways and not an aquatic dinosaur.

An innate immune system signaling pathway in planarians has a dual role: it enhances apoptosis during bacterial infection, but represses apoptosis during tissue regeneration in the absence of infection.

Neuromesodermal and lateral/ventral mesoderm progenitors represent distinct committed states, governed by separate regulatory logics.