Browse our latest Cancer Biology articles

Page 21 of 88
    1. Cancer Biology
    2. Medicine

    Open-top Bessel beam two-photon light sheet microscopy for three-dimensional pathology

    Won Yeong Park, Jieun Yun ... Ki Hean Kim
    Open-top Bessel beam two-photon light sheet microscopy have the potential for rapid and accurate nondestructive pathology by visualizing 3D histological information.
    1. Cancer Biology

    Disassembly of embryonic keratin filaments promotes pancreatic cancer metastases

    Ryan R. Kawalerski, Mariana Torrente Gonçalves ... Luisa F. Escobar-Hoyos
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Cancer Biology
    2. Microbiology and Infectious Disease

    Identification of fallopian tube microbiota and its association with ovarian cancer

    Bo Yu, Congzhou Liu ... David N Fredricks
    A prospective study of intraoperative swab collections from 187 patients identified a putative fallopian tube microbiota and a clear shift in ovarian cancer patients compared to non-cancer patients.
    1. Cancer Biology

    Nifuroxazide suppresses PD-L1 expression and enhances the efficacy of radiotherapy in hepatocellular carcinoma

    Tiesuo Zhao, Pengkun Wei ... Huijie Jia
    A cellular experiment and animal model reveals that nifuroxazide can inhibit the expression of PD-L1 through the proteasome pathway, rather than at the genetic level.
    1. Biochemistry and Chemical Biology
    2. Cancer Biology

    A methylation-phosphorylation switch controls EZH2 stability and hematopoiesis

    Pengfei Guo, Rebecca C Lim ... Hui Zhang
    EZH2 is regulated by a K20-methylation dependent proteolysis and this proteolysis process is negatively controlled by AKT-mediated S21 phosphorylation to establish a methylation-phosphorylation switch to control the PRC2 activity and hematopoiesis.
    1. Cancer Biology

    Molecular classification and tumor microenvironment characteristics in pheochromocytomas

    Sen Qin, Yawei Xu ... Zheng Zhang
    ScRNA-seq of diverse pheochromocytoma patients reveals distinct microenvironment characteristics and supports an informative molecular classification system.
    1. Cancer Biology

    Large pan-cancer cell screen coupled to (phospho-)proteomics underscores high-dose vitamin C as a potent anti-cancer agent

    Andrea Vallés-Martí, Franziska Böttger ... Connie R Jiménez
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Cancer Biology

    A novel triptolide analog downregulates NF-κB and induces mitochondrial apoptosis pathways in human pancreatic cancer

    Qiaomu Tian, Peng Zhang ... Anita S Chong
    CK21 emerges as a compelling candidate for pancreatic cancer treatment, and its capacity to target the NF-κB pathway, induce mitochondrial-mediated apoptosis, and do so with minimal toxicity is a significant stride in the quest for improved therapies.
    1. Cancer Biology

    Ferredoxin 1 is essential for embryonic development and lipid homeostasis

    Shakur Mohibi, Yanhong Zhang ... Xinbin Chen
    The iron-sulfur cluster containing Ferredoxin 1 (FDX1), critical in steroidogenesis and TCA cycle, is required for mammalian embryonic development and maintenance of lipid homeostasis at cellular and organismal levels.
    1. Cancer Biology
    2. Genetics and Genomics

    Single-cell sequencing highlights heterogeneity and malignant progression in actinic keratosis and cutaneous squamous cell carcinoma

    Dan-Dan Zou, Ya-Zhou Sun ... Xin Li
    A single-cell RNA profiling analysis has delineated the molecular changes driving the progression from actinic keratosis to cutaneous squamous cell carcinoma.