Browse our latest Cell Biology articles

The major cytosolic yeast peroxiredoxin Tsa1 controls aging and H₂O₂-resistance by inhibiting protein kinase A through a conserved cysteine in the catalytic subunit activation loop and not by scavenging H₂O₂.

Actinonin kills malaria parasites by targeting the apicoplast-associated metalloprotease FTSH1.

In vitro reconstitution of the core focal adhesion proteins talin and vinculin with actin reveals lipid-dependent release of autoinhibition.

Ribosome collisions along an mRNA are shown to recruit factors that prevent additional ribosomes from initiating translation on that mRNA, thereby providing time to resolve the collision.

Farrerol promotes the efficiency of CRISPR/Cas9-mediated genome editing in both cells and embryos.

Different RhoA and Rac1 dynamics at the cell front and rear are coordinated through periodic GTPase waves, which define the minimal autonomous biochemical machinery necessary and sufficient for cell migration.

Increasing endoplasmic reticulum (ER)–mitochondria contact sites leads to neurodegeneration.

In Caenorhabditis elegans, dendrites establish their unique microtubule polarity by localizing an organizing center behind the growing tip.

Quantitative analyses of yeast P bodies reveals a small number of highly concentrated proteins and many weakly concentrated proteins, suggesting that the compartments are compositionally simpler than previously thought.

The presented primary epithelial acinus-based platform for studying interactions between normal and malignant cells will enable in depth analysis of the tumor initiation process on a molecular level.