Browse our latest Cell Biology articles

Page 309 of 327
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    A RanGTP-independent mechanism allows ribosomal protein nuclear import for ribosome assembly

    Sabina Schütz, Ute Fischer ... Vikram G Panse
    The Tsr2 carrier protein connects the nuclear import machinery with the ribosome assembly pathway.
    1. Cell Biology

    Epsin deficiency impairs endocytosis by stalling the actin-dependent invagination of endocytic clathrin-coated pits

    Mirko Messa, Rubén Fernández-Busnadiego ... Pietro De Camilli
    Epsin has a key role in the coupling of actin to endocytic clathrin coated pits that is required for their maturation and helps capture SNAREs at endocytic clathrin coated pits.
    1. Cell Biology
    2. Chromosomes and Gene Expression

    Histone supply regulates S phase timing and cell cycle progression

    Ufuk Günesdogan, Herbert Jäckle, Alf Herzig
    Controlling cell cycle progression in a developing embryo directly depends on de novo histone supply and a specialized surveillance mechanism for nucleosome assembly.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    MicroRNA-mediated repression of nonsense mRNAs

    Ya Zhao, Jimin Lin ... Ligang Wu
    microRNAs can serve as a surveillance system to repress nonsense mRNAs by recognizing miRNA-responsive elements in the open reading frame region downstream of the premature termination codon.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Mutations: Stop that nonsense!

    Catherine L Jopling
    Version of Record
    Insight
    1. Cell Biology
    2. Developmental Biology

    Microtubules provide directional information for core PCP function

    Maja Matis, David A Russler-Germain ... Jeffrey D Axelrod
    The Fat/Dachsous/Four-jointed (Ft/Ds/Fj) system provides a spatial signal to organize core PCP proteins via the polarization of microtubules.
    1. Structural Biology and Molecular Biophysics
    2. Cell Biology

    A tethered delivery mechanism explains the catalytic action of a microtubule polymerase

    Pelin Ayaz, Sarah Munyoki ... Luke M Rice
    Using linked TOG domains that each bind a curved conformation of αβ-tubulin, a microtubule polymerase catalyzes fast elongation by concentrating αβ-tubulin near the polymer end.
    1. Cell Biology
    2. Developmental Biology

    The Drosophila F-box protein Fbxl7 binds to the protocadherin Fat and regulates Dachs localization and Hippo signaling

    Justin A Bosch, Taryn M Sumabat ... Iswar K Hariharan
    The F-box protein Fbxl7 is a direct effector of the protocadherin Fat and functions in downstream pathways that regulate tissue shape and size.
    1. Cell Biology
    2. Chromosomes and Gene Expression

    Methylation of histone H3K23 blocks DNA damage in pericentric heterochromatin during meiosis

    Romeo Papazyan, Ekaterina Voronina ... Sean D Taverna
    A previously unappreciated histone methylation pathway helps limit DNA double-strand break formation and recombination in heterochromatin during meiosis.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Calmodulin-controlled spatial decoding of oscillatory Ca2+ signals by calcineurin

    Sohum Mehta, Nwe-Nwe Aye-Han ... Jin Zhang
    The ability of calcium waves to exert different effects on calcineurin activity depending on subcellular location is mediated by the distribution of calmodulin.