Browse our latest Cell Biology articles

Page 37 of 316
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    MEMO1 binds iron and modulates iron homeostasis in cancer cells

    Natalia Dolgova, Eva-Maria E Uhlemann ... Oleg Y Dmitriev
    Cancer metastasis modulator MEMO1 binds iron and is involved in regulating iron homeostasis in cancer cells.
    1. Cell Biology

    Pigmentation level of human iPSC-derived RPE does not indicate a specific gene expression profile

    Yoko Nakai-Futatsugi, Jianshi Jin ... Masayo Takahashi
    Pigmentation that confers protective function of RPE is not underlaid by a specific gene expression profile, reviled by microscopic imaging together with single-cell RNA sequencing.
    1. Cell Biology
    2. Neuroscience

    Synapsin E-domain is essential for α-synuclein function

    Alexandra Stavsky, Leonardo A Parra-Rivas ... Daniel Gitler
    Alpha-synuclein binding to the synapsin E-domain is essential and sufficient for their cooperation in attenuating synaptic-vesicle trafficking and neurotransmission.
    Version of Record
    Short Report
    • Important
    • Compelling
    1. Cell Biology
    2. Stem Cells and Regenerative Medicine

    Novel 3D Approach to Model Non-Alcoholic Fatty Liver Disease using human Pluripotent Stem Cells

    Carola Maria Morell, Samantha Grace Tilson ... Ludovic Vallier
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Cell Biology

    Septin 7 interacts with Numb to preserve sarcomere structural organization and muscle contractile function

    Rita De Gasperi, Laszlo Csernoch ... Christopher P Cardozo
    Genetic reduction of Numb or Numb/Nubl is linked to deterioration of the Septin cytoskeleton and suggests cytoskeletal abnormalities are the consequences of and contribute to age-related changes in skeletal muscle.
    1. Cell Biology

    BMP signaling maintains auricular chondrocyte identity and prevents microtia development by inhibiting protein kinase A

    Ruichen Yang, Hongshang Chu ... Baojie Li
    Uncovering a new function of BMP signaling and enhancing our comprehension of the pathogenesis of microtia.
    1. Cancer Biology
    2. Cell Biology

    Loss of tumor suppressor TMEM127 drives RET-mediated transformation through disrupted membrane dynamics

    Timothy J Walker, Eduardo Reyes-Alvarez ... Lois M Mulligan
    TMEM127 depletion alters membrane dynamics, promoting cell surface accumulation and constitutive activity of growth factor receptors, and ultimately providing a novel paradigm for oncogenesis through aberrant receptor localization and signaling.
    1. Cancer Biology
    2. Cell Biology

    N-cadherin directs the collective Schwann cell migration required for nerve regeneration through Slit2/3-mediated contact inhibition of locomotion

    Julian JA Hoving, Elizabeth Harford-Wright ... Alison C Lloyd
    N-cadherin and Slit2/3/Robo interactions provide the outward force to drive collective Schwann cell migration during nerve regeneration, identifying a dual role for N-cadherin in both adhesion and repulsion processes during Schwann cell collective migration.
    1. Cell Biology
    2. Neuroscience

    KIS counteracts PTBP2 and regulates alternative exon usage in neurons

    Marcos Moreno-Aguilera, Alba M Neher ... Carme Gallego
    KIS, a kinase upregulated in the developmental brain, phosphorylates the PTBP2 splicing complex and modulates alternative exon usage for proper synaptic spine emergence and maturation.
    1. Cell Biology

    Distinct transcriptomic profile of satellite cells contributes to preservation of neuromuscular junctions in extraocular muscles of ALS mice

    Ang Li, Jianxun Yi ... Jingsong Zhou
    The distinct transcriptomic features of extraocular muscle satellite cells, partially mimicked by NaBu treatment, endow enhanced self-renewal and axon attraction, contribute to neuromuscular junction preservation during ALS progression.