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    1. Cell Biology

    The insulin / IGF axis is critically important for controlling gene transcription in the podocyte

    Jennifer A Hurcombe, Lusyan Dayalan ... Richard JM Coward
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Solid
    1. Cell Biology
    2. Neuroscience

    Auditory Hair Cells: Examining the role of lipids in hearing

    Yein Christina Park, Angela Ballesteros
    The asymmetry of lipid membranes is tightly regulated in eukaryotic cells, and auditory hair cells are no exception.
    Version of Record
    Insight
    1. Cell Biology
    2. Microbiology and Infectious Disease

    Physiological febrile heat stress increases cytoadhesion through increased protein trafficking of Plasmodium falciparum surface proteins into the red blood cell

    David Jones, Hugo Belda ... Moritz Treeck
    Fever, often seen as protective, accelerates protein export to surfaces of malaria-infected RBCs, increasing adhesion linked to disease severity.
    Version of Record
    Research Article
    • Important
    • Compelling
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    1. Cell Biology

    Regulation of sphingolipid synthesis by the C2H2 zinc finger transcription factor Com2 through ubiquitin-proteasome mediated degradation pathway

    Kosei Matsumoto, Ayane Nagai ... Mitsuaki Tabuchi
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    • Solid
    1. Cell Biology
    2. Developmental Biology

    ZNHIT1-dependent H2A.Z deposition at meiotic prophase I underlies pachytene gene expression and meiotic progression during male meiosis

    Shenfei Sun, Yamei Jiang ... Xinhua Lin
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Cell Biology

    Winding-Up of Fibrin Fibers as a Novel Mechanism of Platelet-Mediated Fiber Compaction

    Alexei Grichine, Tatiana Kovalenko ... Karin Sadoul
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Cell Biology

    Actin-membrane interface stress regulates Arp2/3-branched actin density during lamellipodial protrusion

    Mitchell T Butler, Max A Hockenberry ... James E Bear
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Compelling
    1. Cell Biology
    2. Neuroscience

    Age-dependent H3K9 trimethylation by dSetdb1 impairs mitochondrial UPR leading to degeneration of olfactory neurons and loss of olfactory function in Drosophila

    Francisco Muñoz-Carvajal, Nicole Sanhueza ... Felipe A Court
    Age-related epigenetic regulation of mitochondrial stress responses drives neuronal degeneration and sensory decline, highlighting mitochondrial resilience as a potential target to preserve brain function during aging.
    1. Cell Biology
    2. Physics of Living Systems

    Sarcomere dynamic instability and stochastic heterogeneity drive robust cardiomyocyte contraction

    Daniel Haertter, Lara Hauke ... Christoph F Schmidt
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Cell Biology
    2. Developmental Biology

    A novel 3D visualization method in mice identifies the periportal lamellar complex (PLC) as a key regulator of hepatic ductal and neuronal branching morphogenesis

    Tongtong Xu, Fujun Cao ... Chengjian Zhao
    A high-resolution 3D imaging platform reveals the periportal lamellar complex as a novel structural feature in the mouse liver, regulating bile duct and nerve migration during fibrosis.
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