Proteome-scale visual screening in budding yeast provides a functional catalog of plasma membrane repair proteins and reveals the coordinated cellular responses at the bud tip and the damage site.
A conserved glucagon signaling pathway links high-fat diet-induced metabolic imbalance to cardiac arrhythmia through hormone-producing cells and heart-innervating neurons that regulate rhythmicity.
Distal renal tubular acidosis induced by some SLC4A1 variants is characterized by cytosolic pH alkalization, reduced ATP synthesis and defective autophagy degradative flux.
