Inflammatory activation of endothelial cells triggers Pink1-dependent mitophagy and mitochondrial formyl peptides release, which drives neutrophil recruitment and lung injury.
Krassimira A Garbett, James P Allen ... Richard C Sando
Long-term live imaging and tracking approaches reveal a coordination between excitatory and inhibitory synapse assembly, despite continual spatiotemporal dynamics.
Endosomes operate several exit routes that sort protein cargo and depend on pathway-specific associations of a PROPPIN with the responsible protein coat, such as the here identified CROP2, to support the departure of the cargo carriers.
Fangrui Guo, Roberto Ornelas Guevara ... Guy Tran Van Nhieu
Through low levels of extracellular ATP, EPEC induces small, rapid and coordinated Ca2+ responses in epithelial cells, a yet unreported pattern, that down-regulate inflammation at the onset of infection.
