Browse our latest Cell Biology articles

Page 5 of 333
    1. Cell Biology

    Disruption of sphingolipid metabolism promotes tau seeding through endolysosomal membrane rigidification and rupture

    Jessica Tittelmeier, Carl Alexander Sandhof ... Carmen Nussbaum-Krammer
    Restoring endolysosomal membrane fluidity limits tau seed escape, seeded aggregation, and neuronal toxicity in cell and animal models.
    1. Cell Biology
    2. Chromosomes and Gene Expression

    A genetic toolkit for stable transgenesis in the anaerobic gut parasite Blastocystis ST7-B

    M Rey Toleco, Kevin SW Tan, Mark van der Giezen
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Convincing
    1. Cell Biology
    2. Neuroscience

    ATP8B1–TMEM30B Flippase Activity Maintains Stereocilia Lipid Asymmetry Required for Hearing

    Henry N De Hoyos, Sihan Li ... Jung-Bum Shin
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Compelling
    1. Cell Biology
    2. Neuroscience

    Terminal Schwann Cells Regulate Presynaptic Vesicle Homeostasis but Not Neuromuscular Junction Integrity in Mice

    Hyun Kim, Seon-Yong Kim ... Young-Yun Kong
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Cell Biology

    High basal autophagic activity in the brain revealed by systemic quantitative analysis using GFP-LC3-RFP mice

    Yuki Kanda, Tomoya Eguchi ... Noboru Mizushima
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Cell Biology

    Mitochondrial-derived compartments buffer outer membrane protein load during acute mitochondrial adaptation

    Bo J Price, Sai Sangeetha Balasubramaniam, Adam L Hughes
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Cell Biology

    Ferroptosis is executed through caspase-5 cleavage of gasdermin E in ovarian cancer cells

    Mahmuda Akter, Lei Sun ... Shuang Huang
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Cell Biology

    Targeting Lysosomal MCOLN1/TRPML1 Ion Channels to Finely Alleviate Diabetes Mellitus via a Ca2+- CaMKKβ-AMPK pathway

    Jiaxuan Zhu, Zhaonan Pan ... Dan Li
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Inadequate
    1. Cell Biology

    Prophase Chromosomes Relocalization to Nuclear Periphery in NPP-3/NUP205 Depletion Protects Genome Stability

    Ling Jiang, Yu Chung Tse, Karen Wing Yee Yuen
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Cell Biology
    2. Immunology and Inflammation

    MOTS-c is a mitochondrial-encoded interferon-linked host defense peptide

    Michelle C Rice, Maria Imun ... Changhan Lee
    MOTS-c, a mitochondrial-encoded microprotein, has immunological origins and functions, revealing for the first time that our immune system is encoded by both co-evolved nuclear and mitochondrial genomes.