Browse our latest Cell Biology articles

The RNA-binding protein BICC1 can act as a genetic disease modifier for kidney cyst formation, potentially explaining the high variability of disease onset and severity in autosomal-dominant polycystic kidney disease patients.

Three newly developed biosensors demonstrate that the C-terminal tail of α-tubulin does not freely extend from the microtubule surface as widely thought, but rather is inaccessible along most microtubules in cells.

Small-molecule mitochondrial transcription factor A modulators stabilize mtDNA, preventing cytosolic escape and suppressing cGAS-STING interferon signaling, while improving bioenergetics and fibrosis markers in disease models.

An accessible light-sheet microscope delivers subcellular-resolution, multicolor volumetric, and live-cell imaging, lowering barriers to state-of-the-art performance.

The carboxyl-terminal alanine-threonine-tailed protein ATP5α helps glioblastoma mitochondria maintain a high membrane potential and keep the permeability transition pore closed, thereby promoting tumor growth and increasing resistance to apoptosis.

Upregulation of the β subunit of translation initiation factor eIF2 underlies autophagy suppression and premature aging caused by disruption of axonal transport of mitochondria.

A dynamic, community-driven knowledge repository reduces research costs and accelerates scientific discovery by sharing validated reagent data, negative results, and protocols while rewarding contributors through formal authorship recognition.

Single-cell transcriptomic analysis of the murine testicular interstitium across the lifespan reveals Cd34⁺/Sox4⁺ mesenchymal cells as Leydig progenitors, whose aging-associated decline in glutathione and Sox4-regulated regenerative capacity inform potential therapeutic strategies for age-related testicular dysfunction.