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    1. Cell Biology
    2. Neuroscience

    CO2-dependent opening of connexin 43 hemichannels

    Valentin Mihai Dospinescu, Alexander Mascarenhas ... Nicholas Dale
    Connexin43 is the most ubiquitously expressed connexin in the human body, and the CO2-dependent opening of Connexin43 hemichannels implies that CO2 may influence many physiological processes.
    1. Cell Biology
    2. Chromosomes and Gene Expression

    Intron Retention Controls Localization of lncRNAs PURPL and MALAT1 to Promote Cell Proliferation and Migration

    Ioannis Grammatikakis, Chosita Norkaew ... Ashish Lal
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    • Compelling
    1. Cell Biology
    2. Physics of Living Systems

    The titin N2A-MARP signalosome constrains muscle longitudinal hypertrophy in response to stretch

    Robbert van der Pijl, Jochen Gohlke ... Coen Ottenheijm
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Cell Biology
    2. Neuroscience

    A validated antibody toolbox for ALS research

    Riham Ayoubi, Emma J MacDougall ... Carl Laflamme
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Cell Biology

    Photo-downregulation of SIRT4 mitigates aging in mice by enhancing H3K9ac via fatty acid metabolism

    Fangqing Deng, Rong Yang ... Lianbing Zhang
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Cell Biology

    Decoupling AMPK from fatty acid synthesis allows maintenance of fitness late in life

    Hanane Hadj-Moussa, Megan Ulusan ... Jonathan Houseley
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Cell Biology

    Ubiquitin ligase ITCH regulates life cycle of SARS-CoV-2 virus

    Qiwang Xiang, Camille Wouters ... Jiou Wang
    ITCH is an important regulator of SARS-CoV-2 life cycle, coordinating ubiquitination, assembly, autophagosome-mediated secretion, and spike stability, highlighting ITCH as a promising therapeutic target for antiviral intervention.
    1. Cell Biology
    2. Immunology and Inflammation

    Digest before Ingest: Early Recruitment of Membrane-bound DNaseX to Phagocytic Cups in Macrophages

    Arghajit Pyne, Vivek Pandey ... Xuefeng Wang
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Cell Biology
    2. Chromosomes and Gene Expression

    Transitory enhancement of GATA2 chromatin engagement during early erythroid differentiation

    John W Hobbs, Samuel J Taylor ... Robert A Coleman
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Cell Biology

    Thermogenic Adipose ADH5 Counteracts Age-related Metabolic Decline

    Sara C Sebag, Tate Neff ... Ling Yang
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
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