Browse our latest Chromosomes and Gene Expression articles

Larger phylogenetic context is required to understand human and nonhuman primate brain evolution.

Fission yeast loses its heterochromatin stability at mating-type locus under high temperature due to compromised binding between heterochromatin protein Swi6^HP1 and Atf1.

A novel family of nucleolus-enriched ncRNAs forms allele-specific territories on the nucleolar organizing region (NOR)-containing acrocentric chromosomes.

MukBEF selectively loads onto newly replicated DNA, and MatP prevents MukBEF activity, correlating with matS sites, likely due to MatP-mediated unloading.

Replication origins in yeast are more widespread than previously believed.

The identification of a SUMO E3 ligase engaged in lncRNA transcription, subsequently leading to target-directed small RNA degradation, reveals an unexplored layer of regulatory mechanisms within small RNA-directed chromatin regulation.

A broad, live imaging-based survey of intrinsic protein disorder in Drosophila transcription factors reveals a limited role for their contribution to the protein clustering observed at enhancers.

Mitochondrial RNAs attach to chromatin and regulate nuclear transcription in endothelial stress response.

The binding of transcription factors to mesoscale chromatin fibers leads to microdomains whose features are dependent on the linker DNA length, linker histone density, and tail acetylation levels.

SCA-seq enables simultaneous detection of spatial interactions, chromatin accessibility, and CpG methylation at single-molecule resolution, advancing multi-omics studies of genome spatial organization.