Browse our latest Computational and Systems Biology articles

A biophysical model of the process by which bacteria transition from the motile planktonic state to the immobilized biofilm state yields testable predictions in terms of two dimensionless parameters, one describing nutrient availability and the other describing cellular dispersal.

A new model helps to predict under which conditions a species of bacteria will switch to a static lifestyle.

Gender gaps in academic achievement are in fact "parenthood gender gaps", with mothers experiencing higher levels of work-family conflict, and receiving lower levels of partner support, than fathers.

An automated platform for cell culture combines robotics and artificial intelligence to optimize cell culture protocols and reliably produce specific cell types that could be used for regenerative medicine treatments.

A new mathematical method has been developed, implemented and validated for the analysis of time-lapse confocal laser scanning microscopy images to characterize the swimming behavior of bacterial swimmers moving in the exogenous matrix of pathogenic biofilms.

Both human and microbe cell-free RNA features in plasma could distinguish tumors of different primary locations.

Increased usability and validity of neuroscience models, through FAIR workflows for the whole modeling process, including data and model management, parameter estimation, uncertainty quantification, and model analysis.

Structural differences in adolescent brains associated with binge drinking might be preceding the onset of such behavior, suggesting a reevaluation of studies of the effects of alcohol on the adolescent brain.

A genome-wide map of human allele-specific methylation using long-read sequencing detects novel imprinted DNA methylation events and reveals large blocks of subtle parent-of-origin bias in DNA methylation with mutual exclusive allelic H3K36me3 and H3K27me3 histone modifications.

A new computational approach for detecting sleep waveforms reveals that the 11–15 Hz sleep 'spindle', a neural rhythm implicated in memory consolidation, co-occurs widely across cortex much more often than previously thought.